ArticleGigaScience2025
The haplotype-resolved T2T genome for Bauhinia × blakeana sheds light on the genetic basis of flower heterosis.
Article in GigaScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- From assemblies to ancestry: Genomic advances illuminates legume evolution.Genetics and molecular biology · 2026Article
- The haplotype-resolved T2T genome for Bauhinia × blakeana sheds light on the genetic basis of flower heterosis.GigaScience · 2025Article
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13 authors.
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Abstract
backgroundThe Hong Kong orchid tree Bauhinia × blakeana Dunn has long been proposed to be a sterile interspecific hybrid exhibiting flower heterosis when compared to its likely parental species, Bauhinia purpurea L. and Bauhinia variegata L. Here, we report comparative genomic and transcriptomic analyses of the 3 Bauhinia species.
findingsWe generated chromosome-level assemblies for the parental species and applied a trio-binning approach to construct a haplotype-resolved telomere-to-telomere (T2T) genome for B. blakeana. Comparative chloroplast genome analysis confirmed B. purpurea as the maternal parent. Transcriptome profiling of flower tissues highlighted a closer resemblance of B. blakeana to its maternal parent. Differential gene expression analyses revealed distinct expression patterns among the 3 species, particularly in biosynthetic and metabolic processes. To investigate the genetic basis of flower heterosis observed in B. blakeana, we focused on gene expression patterns within pigment biosynthesis-related pathways. High-parent dominance and overdominance expression patterns were observed, particularly in genes associated with carotenoid biosynthesis. Additionally, allele-specific expression analysis revealed a balanced contribution of maternal and paternal alleles in shaping the gene expression patterns in B. blakeana.
conclusionsOur study offers valuable insights into the genome architecture of hybrid B. blakeana, establishing a comprehensive genomic and transcriptomic resource for future functional genetics research within the Bauhinia genus. It also serves as a model for exploring the characteristics of hybrid species using T2T haplotype-resolved genomes, providing a novel approach to understanding genetic interactions and evolutionary mechanisms in complex genomes with high heterozygosity.
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