Evidence map›Paper›PMID 40276827›Full record

ReviewThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi2025

[Pharmacologic Treatment of Irritable Bowel Syndrome with Predominant Constipation].

Dong Hyun Kim, Hyo Yeop Song, Kwangwoo Nam, Korean Society of Neurogastroenterology and Motility

Abstract readEnglish AbstractReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dong Hyun KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Hyo Yeop SongDepartment of Internal Medicine and Digestive Disease Research Institute, Wonkwang University School of Medicine, Iksan, Korea.
Kwangwoo NamDepartment of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.ORCID 0000-0003-3720-9820
Korean Society of Neurogastroenterology and Motility

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irritable bowel syndrome with predominant constipation (IBS-C) is a functional gastrointestinal disorder characterized by abdominal pain with chronic constipation and abdominal bloating, which could significantly impair the quality of life of patients and bring substantial socio-economic burdens. Pharmacology treatment is central to managing patients with IBS-C, aiming to alleviate symptoms and improve patient treatment outcomes. Guanylate cyclase-C agonists (linaclotide and plecanatide) enhance intestinal fluid secretion and motility, normalize bowel movements, and reduce abdominal pain. Na

Indexed as

ConstipationIrritable Bowel SyndromeAbdominal PainBenzofuransGastrointestinal AgentsGuanylyl Cyclase C AgonistsHumansIsoquinolinesLaxativesLubiprostoneNatriuretic PeptidesPeptidesPolyethylene GlycolsQuality of LifeSelective Serotonin Reuptake InhibitorsSerotonin 5-HT4 Receptor AgonistsBenzofuransGastrointestinal AgentsGuanylyl Cyclase C AgonistsIsoquinolinesLaxativeslinaclotideLubiprostoneNatriuretic PeptidesPeptidesplecanatidePolyethylene GlycolsprucaloprideSelective Serotonin Reuptake InhibitorsSerotonin 5-HT4 Receptor AgonistsSulfonamidestenapanorAntidepressive agentsConstipationGuanylate cyclaseIrritable bowel syndromeSerotonin 5-HT4 receptor agoniststricyclic

Identifiers

PMID40276827
PMCPMC12285454

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.