ArticleFrontiers in chemistry2025
Antioxidant activity and selective cytotoxicity in HCT-116 and WI-38 cell lines of LC-MS/MS profiled extract from
Article in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Dual Functional Properties of Tiliacora acuminata: from Jaundice-related Enzyme Targeting to Green Synthesized Silver Nanoparticles and their Applications in Textile Dye Remediation.Applied biochemistry and biotechnology · 2026Article
- Uncovering the potential anti-cancer compounds from Strobilanthes cusia against colorectal cancer through network pharmacology and molecular docking.Scientific reports · 2026Article
- Astragalin: A promising herbal compound with broad anticancer potential (Review).Oncology letters · 2026Review
- Extracts of the Algerian FungusJournal of fungi (Basel, Switzerland) · 2025Article
- Unseparated Olive Pruning Waste as a Sustainable Feedstock: DoE-Optimized Extracts with Antioxidant Activity Equivalent to Isolated Leaves.Antioxidants (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Methods: Bioactive compounds, including phenolic acids and flavonoids, in various ethyl acetate fractions from the extracted roots and aerial parts, were identified using LC-MS/MS. Principal leaf constituents characterized included Rutin, Resveratrol, Astragalin, and others. The Rutin, Resveratrol, Astragalin, (of ethyl acetate fraction), leaves, and roots were screened for antioxidant activity using DPPH, FRAP, ABTS, and CUPRAC activity assays, as well as for cytotoxicity with the MTT assay. Result: The antioxidant and anticancer activities of the samples were evaluated using DPPH, ABTS, FRAP, CUPRAC assays, and the MTT assay. Roots and Rutin consistently exhibited the strongest antioxidant activity across all assays, with Roots (IC Conclusion: The results provide useful information concerning the medicinal potentials of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.