Evidence map›Paper›PMID 40276769›Full record

ArticleiScience2025

Downregulation of rRNA synthesis by BCL-2 induces chemoresistance in diffuse large B cell lymphoma.

Alessandra Rossi, Saveria Mazzara, Dorotea Salemi, Simone Zanetti, Maria Rosaria Sapienza, Stefania Orecchioni, Giovanna Talarico, Paolo Falvo, Alessandro Davini, Claudio Ceccarelli and 16 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Alessandra RossiOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.
Saveria MazzaraDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Dorotea SalemiOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.
Simone ZanettiOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.
Maria Rosaria SapienzaDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Stefania OrecchioniLaboratory of Hematology-Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Giovanna TalaricoLaboratory of Hematology-Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Paolo FalvoLaboratory of Hematology-Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Alessandro DaviniOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.
Claudio CeccarelliDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Giovanna MottaDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Federica MelleDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Valentina TabanelliDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Claudio AgostinelliDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Davide TrerèDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Marianna PenzoDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Chiara CorsiniLaboratory of Hematology-Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Elena BaiardiOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.
Angelica CalleriDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Umberto VitoloMultidisciplinary Oncology Outpatient Clinic, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.
Francesco BertoliniLaboratory of Hematology-Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Pier Luigi ZinzaniDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy.
Roberto ChiarleDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Corrado TarellaOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.
Stefano PileriDivision of Diagnostic Haematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy.
Enrico DerenziniOncohematology Division, IEO European Institute of Oncology IRCCS, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overexpression of the antiapoptotic oncogene

Indexed as

CancerCell biology

Identifiers

PMID40276769
PMCPMC12020883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.