Evidence map›Paper›PMID 40276416›Full record

ArticleCureus2025

Acute-on-Chronic Pancreatitis in a Patient With Ehlers-Danlos Syndrome: A Rare Association.

Kadi Nguyen, Luisa Ladel, Rebecca Joseph, Seaf Shafique

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kadi NguyenDepartment of Internal Medicine, Larner College of Medicine, University of Vermont, Burlington, USA.
Luisa LadelDepartment of Internal Medicine, Norwalk Hospital, Norwalk, USA.
Rebecca JosephDepartment of Radiology, Norwalk Hospital, Norwalk, USA.
Seaf ShafiqueDepartment of Internal Medicine, Norwalk Hospital, Norwalk, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ehlers-Danlos Syndrome (EDS) is a connective tissue disorder known for its vascular complications, but it is rarely associated with chronic pancreatitis (CP). We describe a 32-year-old female with EDS who presented with acute-on-chronic pancreatitis, following prior episodes of pancreatitis and pseudocyst formation two years prior. This patient's EDS may have predisposed her to recurrent pancreatic inflammation, highlighting the potential role of tissue fragility in pancreatitis susceptibility. This case suggests a need for increased awareness of EDS as a risk factor for pancreatitis and emphasizes the importance of lifestyle counseling to prevent triggers.

Indexed as

chronic pancreatitis (cp)connective tissue disease related complicationsconnective tissue disorderconnective tissue fragilityehlers danlos syndromenecrotizing pancreatitisrecurrent acute pancreatitis

Identifiers

PMID40276416
PMCPMC12021473

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.