Evidence map›Paper›PMID 40276412›Full record

ArticleCureus2025

Symptomatic Treatment of Acute Traveler's Diarrhea With Acupuncture at Stomach 36 (ST36) and Large Intestine 4 (LI4) Acupuncture Points.

Lykourgos Christos Alexakis, Angeliki Konstantinou

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lykourgos Christos AlexakisInternal Medicine, Independent Researcher, Frankfurt, DEU.
Angeliki KonstantinouAnesthesiology, St. Katharinen Hospital, Frankfurt, DEU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traveler's diarrhea is a common occurrence affecting many travelers visiting tropical countries. Antidiarrheal medications are the mainstream treatment. We describe a case of typical traveler's diarrhea in a 44-year-old tourist in Cuba, who was treated with acupuncture in addition to rehydration, without the use of any medication (e.g., antibiotics or anti-motility agents). On the seventh day of the trip, the traveler developed sudden onset, profuse watery diarrhea with mild nausea. During a period of eight hours, the patient passed profuse watery stools five times. Two standard acupuncture needles (0.30 x 30 mm) were inserted by an anesthesiologist trained in acupuncture: one at ST36 (stomach meridian 36) on the left leg and one at LI4 (large intestine meridian 4) on the right hand, for a duration of 30-40 minutes. The exact session was repeated a second time after two days. After each session, a decrease in the frequency (defecation only once per day) and severity of diarrhea (stool consistency improved as per the Bristol scale) was observed. Further research on the effectiveness of ST36 and LI4 points acupuncture and acupressure for the symptomatic management of traveler's diarrhea by means of randomized controlled trials is needed, given the lack of contribution to antimicrobial resistance, the low cost, and the minimal equipment needed for acupuncture and acupressure therapy. If confirmed, such an additional treatment option could be useful in rural, remote, or poor resource settings where the availability of antidiarrheal medications might be limited.

Indexed as

acupuncture therapyacute diarrheadiarrheatraveler’s diarrheatravel medicinetravel-related illness

Identifiers

PMID40276412
PMCPMC12019765

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.