Evidence map›Paper›PMID 40276328›Full record

ArticleEJHaem2025

Immune Thrombocytopenia in an Adult With X-linked Agammaglobulinemia: A Case Report.

Takeaki Matsunaga, Ken Naganuma, Noriko Tanabe, Yoshiko Mori, Marino Nagata, Shuji Momose, Yasushi Kubota

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Takeaki MatsunagaDepartment of Hematology, Saitama Medical Center Saitama Medical University Saitama Japan.
Ken NaganumaDepartment of Hematology, Saitama Medical Center Saitama Medical University Saitama Japan.
Noriko TanabeDepartment of Clinical Genetics, Saitama Medical Center Saitama Medical University Saitama Japan.
Yoshiko MoriDepartment of Clinical Genetics, Saitama Medical Center Saitama Medical University Saitama Japan.
Marino NagataDepartment of Pathology, Saitama Medical Center Saitama Medical University Saitama Japan.
Shuji MomoseDepartment of Pathology, Saitama Medical Center Saitama Medical University Saitama Japan.
Yasushi KubotaDepartment of Hematology, Saitama Medical Center Saitama Medical University Saitama Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with X-linked agammaglobulinemia (XLA), serum immunoglobulins are almost completely lacking. The prevalence of autoimmune diseases is low in XLA compared with other primary immunodeficiency diseases because antibodies are absent in XLA. Immune thrombocytopenia (ITP) is considered an antibody-mediated disease characterized by increased platelet destruction, and adult-onset ITP in XLA has not been reported in detail. The case of a 29-year-old Japanese man with XLA and ITP is described. The patient was treated with prednisolone and intravenous immunoglobulins, resulting in rapid improvement of thrombocytopenia. Clinicians should consider co-existing ITP when progressive thrombocytopenia is observed in a patient with XLA.

Indexed as

Bruton tyrosine kinasehypogammaglobulinemiaimmune thrombocytopeniaplateletX‐linked agammaglobulinemia

Identifiers

PMID40276328
PMCPMC12019708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.