Evidence map›Paper›PMID 40276318›Full record

ArticleJHLT open2025

Outcomes following isolated right ventricular assist device as durable support for primary right heart failure: An INTERMACS analysis.

Edo Y Birati, E Wilson Grandin, Robert S Zhang, Fausto Cabezas, Keshava Rajagopal, Matthew Seigerman, Allison Padegimas, Jeremy A Mazurek, Michael S Kiernan, Navin K Kapur and 9 more

Abstract read
In one paragraph

Article in JHLT open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Edo Y BiratiDivision of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
E Wilson GrandinDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Robert S ZhangDivision of Cardiovascular Medicine, Weill Cornell Medicine, New York, New York.
Fausto CabezasDivision of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Keshava RajagopalDivision of Cardiac Surgery, Department of Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Matthew SeigermanDivision of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Allison PadegimasDivision of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Jeremy A MazurekDivision of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Michael S KiernanDivision of Cardiology, Tufts Medical Center, Boston, Massachusetts.
Navin K KapurDivision of Cardiology, Tufts Medical Center, Boston, Massachusetts.
Pavan AtluriDivision of Cardiothoracic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Guilherme H OliveiraDivision of Cardiology, Tampa General Hospital, Morsani College of Medicine, Tampa, Florida.
Francis D PaganiDivision of Cardiothoracic Surgery, University of Michigan School of Medicine, Ann Arbor, Michigan.
Susan L MyersDivision of Cardiothoracic Surgery, University of Alabama Birmingham School of Medicine, Birmingham, Alabama.
Jeffrey TeutebergDivision of Cardiology, Stanford University Hospital, Palo Alto, California.
Robert L KormosUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
James K KirklinDivision of Cardiothoracic Surgery, University of Alabama Birmingham School of Medicine, Birmingham, Alabama.
Michael A AckerDivision of Cardiothoracic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Jesus Eduardo RameJefferson Bruce and Robbi Toll Heart and Vascular Institute, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outcomes with isolated right ventricular assist devices (iRVAD) using pumps designed for the left ventricle are not well described. This study compares the clinical characteristics and outcomes of iRVAD patients to those patients treated with left ventricular assist device (LVAD) and biventricular assist devices (BiVAD). This study consisted of patients who received iRVAD from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) registry (2006-2017). The primary outcome was 2-year survival. Of 20,789 patients, 26 (0.13%) received iRVAD, 17 with pulsatile flow and 9 with continuous-flow devices. Device strategy was bridge to recovery/rescue therapy in 9 (35%), bridge to transplant/decision in 14 (52%), and destination therapy in 3 (12%). Twelve (46%) patients were INTERMACS profile 1, 5 patients (19%) required extracorporeal membrane oxygenation, and 13 (50%) needed mechanical ventilation. Two-year survival for patients with iRVAD (41.3%) was similar to BiVAD (45.2%) and significantly lower than LVAD (69.0%). In patients with isolated right-sided failure, long-term iRVAD support is feasible.

Indexed as

cardiogenic shockdurable mechanical circulatory supportright heart failureright ventricular assist deviceright ventricular dysfunction

Identifiers

PMID40276318
PMCPMC12018192

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.