ArticleFrontiers in microbiology2025
Integrated metabolomics and intestinal microbiota analysis to reveal anti-post-weaning diarrhea mechanisms of Modified Yupingfeng Granule in Rex rabbits.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Article
- Organic Acids in Rabbit Nutrition: Mechanisms, Advancements, and Potentials for Sustainable Production.Veterinary sciences · 2026Review
- Assessment of kernel oil of Quercus baloot as a natural feed additive for rabbit growth, blood profile, meat quality, and intestinal histomorphology.Tropical animal health and production · 2025Article
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15 authors.
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Abstract
Introduction: Post-weaning Diarrhea (PWD) is a kind of physiological stress diarrhea in Rex rabbits after weaning, which can lead to death in severe cases. Traditional Chinese medicine (TCM) has been widely used in animal due to its advantages of natural origin, diverse functions, safety, reliability, economy and environmental protection. Modified Yupingfeng Granule (MYPFG) is an improved Yupingfeng prescription based on the famous traditional Chinese prescription Yupingfeng (YPF), which is combined with other TCM and has obvious synergistic and additive activity in order to obtain an excellent natural medicine for PWD. Methods: In this study, 120 weaned Rex rabbits were randomly allocated to 4 treatment groups, including control (CON), low dose (LD), medium dose (MD), high dose (HD). Rabbits were fed a control diet or a different MYPFG proportions of diet for 30 days. The study combined 16S rRNA analysis of intestinal microbiota and cecal contents metabolomics to explore the MYPFG effect on weaned Rex rabbits. Results: MYPFG increased average daily gain, villus length to crypt depth ratio and decreased the feed to meat ratio, diarrhea frequency, mortality rate, depth of crypt ( Discussion: MYPFG could regulate intestinal microbiota and change the metabolic pathway of some amino acids to alleviate the PWD in Rex rabbits.
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