ArticleOpen veterinary journal2025
Effect of nanocurcumin administration on superoxide dismutase and progesterone level exposure to noise stress during pregnancy in mice.
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effects of nanocurcumin administration on malondialdehyde and estrogen levels in mice exposed to noise-induced stress.Open veterinary journal · 2026Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Continuous noise with high decibels (dB) intensity continuously can cause psychological stress in a person. Stress during pregnancy can have a negative impact on fetal development; this is due to the narrowing of the placental artery and ends in the obstruction of the flow of nutrients and oxygen to the fetus. Increased cortisol levels during pregnancy stress will signal the placenta to reduce the production of progesterone and estradiol and stimulate the secretion of prostaglandins that activate contractions. Aim: This study aims to determine the effect of nanocurcumin administration on pregnant mice under the stress of 135 dB disturbance for 40 minutes with a continuous pattern. Methods: This experimental study used 25 female mice in five groups: K(-) with no treatment, K(+) with 135 dB disturbance induction for 40 minutes with a continuous pattern, P1 given disturbance and nanocurcumin dose 14 mg/kgBW, P2 given disturbance and nanocurcumin dose 21 mg/kgBW, and P3 given disturbance and nanocurcumin 24.5 mg/kgBW. SOD and progesterone were tested using ELISA. Result: Data analysis using one-way ANOVA followed by the least significant difference. The result of this study conducted nanocurcumin dose of 24.5 mg/kgBW gave the most significant effect ( Conclusion: The conclusion of this study, an administration of nanocurcumin at a dose of 24.5 mg/kgBW, was effective in reducing oxidative stress and increasing progesterone levels in mice that experienced stress due to disorders during pregnancy.
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