Evidence map›Paper›PMID 40276194›Full record

ArticleOpen veterinary journal2025

The beneficial impact of oregano essential oil supplementation on growth, physiological function, antioxidant activity, and immune response in Nile tilapia (

Mohamed A Khallaf, Wesam H Marzouk, Hanan A Ghetas, Haguer M Salah El Din, Mona Assas, Azza Hafez, Alaa Elgaabari, Eman M Moustafa

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohamed A KhallafDepartment of Aquatic Animals Medicine and Management, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt.
Wesam H MarzoukVeterinarian at the General Organization for Veterinary Services in Cairo, Cairo, Egypt.
Hanan A GhetasDepartment of Aquatic Animals Medicine and Management, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt.
Haguer M Salah El DinFish Diseases and Management Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Mona AssasFish processing and Biotechnology Department, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, Egypt.
Azza HafezNutrition and Clinical Nutrition Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Alaa ElgaabariDepartment of Animal Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Eman M MoustafaFish Diseases and Management Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adding oregano essential oil (OEO) as a supplement has great potential to improve fish production efficiency. Aim: Current research was executed to assess the prospective impact of OEO incorporation into tilapia diets on physiological response, growth performance, oxidative capacity, and immune status when subjected to Methods: Three different experimental diets were prepared by augmenting a 30% protein basal diet with OEO at concentrations of 0, 0.5, and 1 g/kg feed. Each of the three treatment groups consisted of sixty fish (three copies of twenty fish each) and was randomly assigned out of 180 healthy Nile tilapia Results: Physiological performance, antioxidant indicators, immunological function (phagocytic activity, lysozyme, and phagocytic index), and growth metrics were all enhanced in fish that were given OEO supplements. Antibiotics may be a new contender: oregano oil, when consumed orally, reduces pathogenic oxidative stress. The villus height, breadth, and depth were enhanced by oregano oil, which also improved intestinal morphology. On the other hand, animals infected with Conclusion: For optimal development, immunity, performance in physiological tests, and gut health, Nile tilapia fingerlings are fed half a gram per kilogram of OEO.

Indexed as

AntioxidantsCichlidsFish DiseasesGram-Negative Bacterial InfectionsOils, VolatileOriganumAeromonas hydrophilaAnimal FeedAnimalsDietDietary SupplementsAntioxidantsOils, VolatileAeromonas hydrophilaNile tilapiaOregano essential oilOxidative status

Identifiers

PMID40276194
PMCPMC12017732

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.