ArticleOpen veterinary journal2025
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Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Molecular insights into the protective role of nano-naringin in mancozeb-induced testicular damage and infertility.Biological research · 2026Article
- Effects of White Bualuang (Biology · 2026Article
- The protective effects of the combination ofOpen veterinary journal · 2025Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A mancozeb, belonging to a pesticide, can induce testicular injury via free radical generation and antioxidant suppression. Aim: This study aimed to compare and evaluate the therapeutic roles of Methods: Testicular toxicity was induced by oral administration of mancozeb (MCZ) at a dose of 313.6 mg/Kg for 4 weeks. Fifty male rats were allocated randomly into 5 groups, each group contained 10 rats. The first group (control group; C), second group (mancozeb group; MCZ) was orally administered 313.6 mg/Kg of mancozeb as a single dose/day for 4 weeks, third group (MCZ+PPE) received MCZ as the second group then administered Results: Testicular follicle-stimulating hormone receptor (FSHr) and luteinizing hormone receptor (LHr) gene expression was significantly upregulated in rats that received PPE + LC+ MCZ compared with the experimental rats. The seminal fluid quality was significantly elevated while abnormal morphology significantly declined in the MCZ+PPE, MCZ+LC, and MCZ+PPE+LC groups compared with the MCZ group. The serum FSH, testosterone, LH, and antioxidant enzymes, superoxide dismutase, and glutathione peroxidase, increased significantly, whereas malondialdehyde decreased significantly in rats that received PPE+ LC+ MCZ compared with all experimental rats. In addition, based on testicular-histopathological investigations, the administration of both PPE and LC, alone or in combination, can improve testicular disarrangement due to mancozeb-induced testicular damage. Conclusion: The administration of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.