Evidence map›Paper›PMID 40276084›Full record

ReviewOncology letters2025

Progress in the development of cancer vaccines for lung cancer utilizing dendritic cells (Review).

Hui Hu, Wen-Jun Chen, Chuang Sun, Jun-Ping Xie

Abstract readReview
In one paragraph

Review in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hui HuDepartment of Respiratory and Critical Care, The Second Affiliated Hospital of Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.
Wen-Jun ChenDepartment of Oncology, PLA Navy Anqing Hospital, Anqing, Anhui 246004, P.R. China.
Chuang SunDepartment of Respiratory and Critical Care, Xinyu People's Hospital, Xinyu, Jiangxi 338099, P.R. China.
Jun-Ping XieDepartment of Respiratory and Critical Care, The Second Affiliated Hospital of Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is a major global health concern in terms of both incidence and mortality. Despite substantial advancements in targeted therapy and immune checkpoint inhibitor treatments, their overall effectiveness is limited. Dendritic cells (DCs) are crucial in innate and acquired immune responses due to their effective presentation of antigens. DC-based cancer vaccines have been identified as promising strategies for personalized cancer immunotherapy. The present review presents a thorough examination of the immunomodulation and associated mechanisms of DC vaccines in lung cancer, with a specific emphasis on the presentation of clinical trial data concerning the safety, feasibility and effectiveness of DC vaccines in the treatment of patients with lung cancer. The objective of this review is to highlight strategies and provide insights that may improve the development and clinical efficacy of DC vaccines for the treatment lung cancer.

Indexed as

dendritic cellsdendritic cell vaccinelung cancer

Identifiers

PMID40276084
PMCPMC12018796

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.