Evidence map›Paper›PMID 40275994›Full record

ReviewIJID regions2025

Assessing the evidence for antibiotic management of laboratory-confirmed

Trudy D Leong, Ameer Sj Hohlfeld, Funeka Bango, Denny Mabetha, Ntombifuthi Blose, Joy Oliver, Mark E Engel, Tamara Kredo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Trudy D LeongHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Ameer Sj HohlfeldHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Funeka BangoHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Denny MabethaHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Ntombifuthi BloseHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Joy OliverHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Mark E EngelCochrane Centre South Africa, South African Medical Research Council, Parowvallei, Cape Town, South Africa.
Tamara KredoHealth Systems Research Unit, South African Medical Research Council, Parowvallei, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are potential sequelae of untreated group A streptococcal ( Methods: We searched PubMed, Scopus, Cochrane Library, and clinical trial registries for published and ongoing trials measuring the eradication of Results: No trials were reported on ARF/RHD outcomes. However, we identified 12 trials and pooled data comparing penicillin, cotrimoxazole, macrolides, and cephalosporins. There was probably no difference between interventions for eradicating Conclusions: The available evidence for directed treatment of

Indexed as

AntibioticsLaboratory-confirmedRheumatic feverRheumatic heart diseaseStreptococcal skin infections

Identifiers

PMID40275994
PMCPMC12019448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.