Evidence map›Paper›PMID 40275987›Full record

ArticleBeilstein journal of nanotechnology2025

Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus.

Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Beilstein journal of nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Carlos Enrique Torres-MéndezDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0003-2841-7724
Sharmilee NandiDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0009-0005-4360-807X
Klara MartinovicDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Patrizia KühneDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Yifan LiuDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.
Sam TaylorDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.
Maria LysandrouDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Maria Ines Berrojo Romeyro MascarenhasDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Viktoria LangwallnerDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Javier Enrique Sebastián AlonsoDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.
Ivana JovanovicDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Maike LüftnerDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Georgia-Vasiliki GkountanaDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-4894-5762
David BernDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.
Abdul-Raouf AtifDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0002-5645-8323
Ehsan Manouchehri DoulabiDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Gemma MestresDivision of Biomedical Engineering, Department of Materials Science and Engineering, Uppsala University, Uppsala, Sweden.
Masood Kamali-MoghaddamDepartment of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An electrochemical biosensor based on modified carbon screen-printed electrodes was developed for the detection of hemagglutinin of influenza A H1N1 virus (H1). Gold nanoflowers were electrodeposited on the electrode to increase conductivity and surface area. The electrochemical signal was amplified by functionalization of the gold nanoflowers with 4-aminothiophenol, which resulted in a 100-fold decrease of the charge transfer resistance due to a tunneling effect. Subsequently, monoclonal antibodies against H1 were immobilized on the surface via covalent amide bond formation, followed by blocking with bovine serum albumin to minimize nonspecific hydrophobic binding. The electrodes were characterized by cyclic voltammetry and electrochemical impedance spectroscopy experiments in the presence of [Fe(CN)

Indexed as

charge transfercyclic voltammetrydifferential pulse voltammetryelectrochemical impedance spectroscopyelectrodeposition

Identifiers

PMID40275987
PMCPMC12018907

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.