Evidence map›Paper›PMID 40275758›Full record

ReviewAddiction (Abingdon, England)2025

Rare but relevant: Hydrocarbons and sudden sniffing syndrome.

Ingrid Berling, Geoffrey Kennedy Isbister

Abstract readReview
In one paragraph

Review in Addiction (Abingdon, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ingrid BerlingClinical Toxicology Research Group, University of Newcastle, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0002-8993-2693
Geoffrey Kennedy IsbisterClinical Toxicology Research Group, University of Newcastle, Newcastle, NSW, Australia.ORCID https://orcid.org/0000-0003-1519-7419

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhaled hydrocarbon-associated sudden collapse (IHASC), often referred to as 'sudden sniffing death syndrome' is a critical and often fatal event linked to the inhalation of volatile hydrocarbons, primarily occurring in adolescents and young adults. This syndrome manifests as sudden cardiac and/or respiratory arrest, typically occurring during or straight after inhalant use, almost always triggered by exertion or emotional distress. The prevalence is (likely) uncommon, but the syndrome concerning, given the young and vulnerable populations engaging in inhalant misuse. Those who collapse while alone are often found deceased, but those with a witnessed collapse and immediate bystander intervention with cardiopulmonary resuscitation (CPR) and defibrillation have good survival rates, far better than from cardiac arrest in general. Ultimately, death from IHASC is preventable with educational initiatives aimed at reducing inhalant misuse, preventative measures aimed at reducing access to commonly misused products, and educating lay people to provide immediate bystander CPR.

Indexed as

Death, SuddenDeath, Sudden, CardiacHydrocarbonsInhalant AbuseAdolescentCardiopulmonary ResuscitationHumansSyndromeYoung AdultHydrocarbonsaerosolarrestcardiac sensitisationhydrocarbonsniffing syndromevolatile

Identifiers

PMID40275758
PMCPMC12319642

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.