ArticleNeurogastroenterology and motility2025
Relationship Between Hemoglobin A1c and Fecal Incontinence in a Nationwide Cohort Study.
Article in Neurogastroenterology and motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Recurrence After Rectopexy: Insights From Magnetic Resonance Defecography.Diseases of the colon and rectum · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
introductionGastrointestinal manifestations of diabetes include a variety of symptoms, including fecal incontinence (FI). We investigated the relationship between hemoglobin A1c and FI among US adults in a large, population-based survey.
methodsWe identified adults (≥ 20 years) who completed the bowel health questionnaire and had A1c data in the National Health and Nutrition Examination Survey from 2005 to 2010 (N = 13,787). FI was defined as any involuntary loss of mucus, liquid, or solid stool during the last 30 days. Adjusted odds ratios (aORs) for FI were estimated in a multivariable logistic model according to A1c. Subgroup analyses examined relevant characteristics.
resultsWe identified 1283 (9.3%) adults with FI. A1c was associated with a 26% increase in the odds of FI (crude OR 1.26, 95% CI 1.20-1.33), which persisted after stepwise adjustment for age, demographic factors, and comorbidities (aOR 1.09, 95% CI 1.01-1.17). In subgroup analyses, A1c was associated with FI in diabetes (aOR 1.13, 95% CI 1.01-1.26), women (aOR 1.15, 95% CI 1.02-1.3), those < 65 years of age (aOR 1.17, 95% CI 1.09-1.25), overweight/obesity (aOR 1.1, 95% CI 1.02-1.20), non-white (aOR 1.1, 95% CI 1.01-1.20), and those with solid stool FI (aOR 1.17, 95% CI 1.04-1.32).
conclusionIncreasing A1c was associated with an increased odds of FI. Our study provides insights into subgroups of patients who may benefit from interventions aimed at glucose control to reduce this risk of FI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.