Evidence map›Paper›PMID 40275477›Full record

Observational studyObesity (Silver Spring, Md.)2025

Perceptions of anti-obesity medications among people with obesity and healthcare providers in the US: Findings from the OBSERVE Study.

Lee M Kaplan, Kimberly Gudzune, Jamy Ard, Rekha Kumar, Nadia N Ahmad, Hong Kan, Tracy J Sims, Jiat Ling Poon, Kristen King-Concialdi, Kathleen Beusterien and 4 more

Abstract readObservational Study
In one paragraph

Observational study in Obesity (Silver Spring, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Lee M KaplanGeisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID https://orcid.org/0000-0002-6301-2696
Kimberly GudzuneJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID https://orcid.org/0000-0002-7782-1769
Jamy ArdWake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-1643-6795
Rekha KumarWeill Cornell Medical College, New York, New York, USA.
Nadia N AhmadEli Lilly and Company, Indianapolis, Indiana, USA.
Hong KanEli Lilly and Company, Indianapolis, Indiana, USA.
Tracy J SimsEli Lilly and Company, Indianapolis, Indiana, USA.
Jiat Ling PoonEli Lilly and Company, Indianapolis, Indiana, USA.
Kristen King-ConcialdiOracle Life Sciences, Austin, Texas, USA.
Kathleen BeusterienOracle Life Sciences, Austin, Texas, USA.
Sheila DrakeleyOracle Life Sciences, Austin, Texas, USA.
Julia P DunnEli Lilly and Company, Indianapolis, Indiana, USA.ORCID https://orcid.org/0000-0001-9561-0183
Scott KahanGeorge Washington University School of Medicine, Washington, District of Columbia, USA.
OBSERVE Study

Funding

Eli Lilly and Company
6 · The paper itself

Abstract

objectiveThe objective of this study was to understand the perceptions of and drivers/barriers to antiobesity medication (AOM) use among people with obesity (PwO) and health care providers (HCPs) in the United States.

methodsIn 2022, PwO and HCPs completed cross-sectional surveys that included questions on perceptions of obesity management and AOMs. Data were analyzed using descriptive statistics.

resultsSurvey participants (1007 PwO and 474 HCPs) emphasized the effectiveness of lifestyle change and the patient's responsibility to address obesity. PwO reported a willingness to take newly approved AOMs long term. HCPs believed that their patients would adhere to AOMs long term if they experienced success. Both PwO and HCPs perceived an increased effectiveness of a multimodal approach to combining AOMs with HCP-guided lifestyle intervention. Potential barriers to long-term use of AOMs for both groups included concerns regarding long-term side effects and outcomes, costs and insurance coverage, and perception of AOMs that do not align with treatment of a chronic disease.

conclusionsPwO and HCPs are interested in new AOM options, but educational gaps remain as a barrier to recommended multimodal chronic care. Ongoing education that includes the known effectiveness and safety data of newer AOMs and pending outcome trials could improve shared decision-making in obesity care.

Indexed as

Anti-Obesity AgentsHealth PersonnelObesityAdultAttitude of Health PersonnelCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansLife StyleMaleMiddle AgedPerceptionSurveys and QuestionnairesUnited StatesAnti-Obesity Agents

Identifiers

PMID40275477
PMCPMC12119403

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.