ArticleWorld journal of surgical oncology2025
Supermicrosurgical lymphaticovenous anastomosis for breast cancer related lymphedema in low resources settings.
Article in World journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSupermicrosurgical lymphaticovenous anastomosis (LVA)is becoming popular for the management of breast cancer-related lymphedema (BCRL), but mainly provided in well-developed countries. Little is known on possibility of LVA with limited resources. This study aimed to evaluate feasibility of LVA in Egypt, where latest devices are not available.
methodsMedical records of patients who underwent LVA for progressive BCRL were reviewed. All patients were refractory to conservative treatment for 6 months or longer. As devices for near-infrared fluorescent lymphography was not available, a conventional high-frequency (18-MHz) ultrasound was used to localize the lymph vessels and veins for LVA. LVA was done using conventional microsurgery sets and 10 - 0 nylon sutures under an operating microscope with 40 times magnification. One-year postoperative results were evaluated based on upper extremity lymphedema index (UEL index), cellulitis frequency, and subjective symptoms.
resultsTwenty-three patients were included. The number of LVAs per limb ranged from 2 to 3 (average, 2). Lymph vessel detection rate was 92.6% (50/54). Ten (43.5%) patients with dermal backflow (DB) showed 19.2% postoperative volume reduction based on UEL index after one year. Thirteen (56.5%) patients without dermal backflow showed only 2% reduction. Postoperative UEL index was significantly lower than preoperative UEL index (123.5 ± 7.3 ml vs. 136.4 ± 9.4 ml, P = 0.017). Postoperative cellulitis frequency was decreased compared to preoperative one (2.15 ± 0.85 vs. 0.09 ± 0.18 attack/year, P ˂ 0.001). 13(56.5%) patients reported improvement in all subjective symptoms; limb tension improvement in 18 (78.3%) patients, limb heaviness in 15 (65.2%), and overall limb mobility in 13 (56.5%).
conclusionsLVA could be safely and effectively performed in limited resources settings without latest device for lymphatic mapping nor supermicrosurgery instruments. A conventional high-frequency ultrasound allows lymphatic and venous mapping useful for LVA. LVA should not be given up even with limited resources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.