Evidence map›Paper›PMID 40275169›Full record

ArticleBMC infectious diseases2025

Human papillomavirus (HPV) infection and liquid-based cytologic tests among cervical screening participants in Shannan City, Tibet, China, during 2021-2022.

Dilu Feng, Yuwei Yao, Xiaowu Zhu, Jun Chen, Yeshe Lhamo, Lamu Baima, Hongbo Wang, Qiyue Wang

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dilu Feng *Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People's Republic of China.
Yuwei Yao *Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People's Republic of China.
Xiaowu ZhuDepartment of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People's Republic of China.
Jun ChenDepartment of Gynecology and Obstetrics, Shannan Maternal and Child Health Hospital, Shannan, Tibet, People's Republic of China.
Yeshe LhamoDepartment of Gynecology and Obstetrics, Shannan Maternal and Child Health Hospital, Shannan, Tibet, People's Republic of China.
Lamu BaimaDepartment of Gynecology and Obstetrics, Shannan Maternal and Child Health Hospital, Shannan, Tibet, People's Republic of China.
Hongbo WangDepartment of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People's Republic of China.
Qiyue WangDepartment of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, People's Republic of China. wangqiyue1@163.com.

Funding

Fundamental Research Funds for the Central Universities 2019kfyXKJC072International Science and technology cooperation project of Hubei Province GJHZ2021000024National Natural Science Foundation of China 81974409
6 · The paper itself

Abstract

backgroundCervical cancer is the most common malignant tumor of the reproductive tract in women and poses a serious threat to their health. Cervical cancer screening is primarily conducted through the detection of HPV or cytological examination. In this study, we analyzed the prevalence, genotyping of HPV, and cervical cytology among women in Shannan city, Tibet, China, between 2021 and 2022, to guide the prevention of cervical cancer among local women. This is the first large-scale cervical cytology screening study conducted in the southern region of the province.

methodsBetween January 2021 and December 2022, 15,493 women participated in HPV genotype testing, and 16,775 women underwent ThinPrep cytologic tests. HPV prevalence and genotype distribution were analyzed for the entire population. Furthermore, the samples were stratified by age group and altitude to analyze the HPV infection rate and distribution of cervical cytological abnormalities.

resultsThe prevalence of HPV in Shannan city was 7.91%, with HPV16 and HPV18 affecting 1.21%. Single infections (95.92%) were more common than multiple infections (4.08%). The overall HPV infection rate peaked in the cohort < 25 years of age (13.25%). Furthermore, HPV infection rates and cervical cell abnormalities varied according to the administrative division in Shannan city, and this difference was attributed to various altitudes.

conclusionAmong HPV carriers, the infection rate peaks in women aged 25 years, after which it declined annually, and the probability of coinfection is relatively low. Additionally, we found that high-altitude areas exhibited elevated HPV prevalence but fewer cervical abnormalities, suggesting complex environmental, genetic, and cultural influences on infection and disease progression. Based on these data, effective recommendations can be made for cervical cancer screening and HPV prevention in local communities.

Indexed as

PapillomaviridaePapillomavirus InfectionsUterine Cervical NeoplasmsAdolescentAdultAgedCervix UteriEarly Detection of CancerFemaleGenotypeHuman Papillomavirus VirusesHumansMass ScreeningMiddle AgedPrevalenceTibetCervical cancer screeningDisease distributionHuman papillomavirus infectionPrevalenceThinprep cytologic tests

Identifiers

PMID40275169
PMCPMC12023534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.