ArticleBMC pregnancy and childbirth2025
Effect of hysteroscopic adhesiolysis for mild intrauterine adhesions on live birth rate following embryo transfer: a retrospective cohort study.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Inflammatory cytokine signatures predict postoperative intrauterine adhesions after hysteroscopic fibroid resection: Evidence from a prospective cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Observational
- Micro-Nano Composite System Combining Mesenchymal Stem Cells and Pirfenidone for Endometrial Regeneration via Microenvironment Remodeling.Advanced healthcare materials · 2026Article
- Perioperative inflammatory response as a determinant of post-myomectomy intrauterine adhesion formation.BMC women's health · 2026Observational
- Correction: Effect of hysteroscopic adhesiolysis for mild intrauterine adhesions on live birth rate following embryo transfer: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Assessing the Reliability of Hysteroscopic Sampling Methods for Diagnosing Atypical Endometrial Hyperplasia.Cancers · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
backgroundNumerous studies have demonstrated that the presence of IUAs can have detrimental effects on female reproductive function, potentially leading to infertility. Hysteroscopic adhesiolysis is widely regarded as the primary treatment for IUAs. A 2021 consensus development study on the top 10 research priorities for the future of infertility suggested that the impact on live birth rates after surgical treatment of mild IUAs is uncertain. MATERIALS AND
methodsThe study was a retrospective cohort study that included 442 patients who were diagnosed with mild IUAs and underwent embryo transfer (fresh or frozen embryo) from January 2017 to December 2023 at a University-based reproductive medical center. Patients were divided into two groups according to whether underwent hysteroscopic adhesiolysis. The non-surgical group consisted of 204 patients, while the surgical group consisted of 238 patients. all patients underwent fresh or frozen embryo transfer. We compared the pregnancy outcomes and obstetric outcomes of the first embryo transfer after diagnosis or surgery of IUAs between the two groups. The main outcome measure is live birth rates. Between-group variances were evaluated using either the Pearson χ² test or the t-test. Multiple logistic regression analyses were applied to control for potential confounding effects.
resultsThere were no significant differences in live birth rates of the non-surgical group and the surgical group(45.1% versus 42.0%,aOR,0.824;95%CI,0.558-1.217;P,0.330).All other pregnancy indicators showed no significant difference between the groups either.
conclusionHysteroscopic adhesiolysis does not significantly improve the live birth rates in patients with mild IUAs. Therefore, for patients with mild IUAs, it is recommended to prioritize expectant treatment. CLINICAL TRIAL NUMBER: Not applicable.
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