Evidence map›Paper›PMID 40275126›Full record

ArticleBMC genomics2025

The blood transcriptome of musk deer under heat stress condition reveals the regulatory mechanism of genes to maintain homeostasis metabolism.

Xin Shi, Zhuo Cheng, Chengli Zheng, Kaiqing Wang, Jiandong Yang, Hang Jie, Yang Li, Ming Zhang

Abstract read
In one paragraph

Article in BMC genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin Shi *College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Zhuo Cheng *College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Chengli ZhengSichuan Institute of Musk Deer Breeding, Chengdu, 611845, China.
Kaiqing WangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Jiandong YangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China.
Hang JieChongqing Institute of Medicinal Plant Cultivation, Yongchuan, Chongqing, 408435, China. jiehangisgood@126.com.
Yang LiChengdu Yongkang Pharmaceutical Co., Ltd, Wenjiang distrct, Chengdu, 611130, China.
Ming ZhangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu, 611130, China. zhangming@sicau.edu.cn.

Funding

Chongqing basic scientific research fund project 2022jk017National Natural Science Foundation of China 81973428Science and Technology Department of Sichuan Province 2023JDR0053
6 · The paper itself

Abstract

backgroundHeat stress has a significant adverse impact on both livestock and poultry production, posing a considerable challenge to the artificial breeding of forest musk deer. However, there is a lack of studies on the heat stress of forest musk deer, so it is necessary to understand the effects of temperature and humidity index (THI) variation on these animals.

resultsIn according to the local climate characteristics, blood samples were collected during four periods (April, June, July and August) for biochemical indicators and transcriptome sequencing. The results showed that blood cortisol and corticosterone concentrations increased significantly in July (THI = 74.89, P < 0.05). Moreover, Na

conclusionsResearch indicates that heat stress disrupts the normal metabolism of forest musk deer and adversely affects their immune system, which is attributed to the THI exceeding the threshold that forest musk deer can tolerate. The findings of this study provide valuable data support for the scientific breeding of captive forest musk deer and enhance the understanding of the immune dynamics of ruminants under heat stress.

Indexed as

DeerHeat-Shock ResponseHomeostasisTranscriptomeAnimalsGene Expression ProfilingGene Expression RegulationCorticosteroneCortisolHeat stressHomeostasis metabolismMusk deer

Identifiers

PMID40275126
PMCPMC12023374

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.