Evidence map›Paper›PMID 40275104›Full record

ArticleNPJ digital medicine2025

Opportunities and risks of artificial intelligence in patient portal messaging in primary care.

Joshua M Biro, Jessica L Handley, J Malcolm McCurry, Adam Visconti, Jeffrey Weinfeld, J Gregory Trafton, Raj M Ratwani

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  12. Ethical considerations for clinical adoption of ambient digital scribe technology.Journal of the American Medical Informatics Association : JAMIA · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua M BiroMedStar Health National Center for Human Factors in Healthcare, Washington, DC, USA. Joshua.M.Biro@medstar.net.
Jessica L HandleyMedStar Health National Center for Human Factors in Healthcare, Washington, DC, USA.
J Malcolm McCurryNaval Research Laboratory, Washington, DC, USA.
Adam ViscontiGeorgetown University Medical Center, Washington, DC, USA.
Jeffrey WeinfeldGeorgetown University Medical Center, Washington, DC, USA.
J Gregory TraftonNaval Research Laboratory, Washington, DC, USA.
Raj M RatwaniMedStar Health National Center for Human Factors in Healthcare, Washington, DC, USA.

Funding

AHRQ HHS R03 HS030307
6 · The paper itself

Abstract

The rapid increase in patient portal messaging has heightened the workload for primary care physicians (PCPs), contributing to burnout. The use of generative artificial intelligence (AI) to draft responses to patient messages has shown promise in reducing cognitive burden, yet there is still much unknown about the safety and perceptions of using AI drafts. This cross-sectional simulation study assessed whether PCPs could identify and correct errors in AI-generated draft responses to patient portal messages. Twenty practicing PCPs reviewed 18 patient portal messages, four of which contained errors categorized as objective inaccuracies or potentially harmful omissions. Each error was insufficiently addressed by 13-15 participants, and 35-45% of erroneous drafts were submitted entirely unedited. While 80% of participants agreed AI drafts reduced cognitive workload and 75% found them safe, uncorrected errors highlight patient safety risks, underscoring the need for improved design, training, and error-detection mechanisms for AI tools.

Identifiers

PMID40275104
PMCPMC12022076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.