Evidence map›Paper›PMID 40275026›Full record

ArticleThe Journal of antibiotics2025

New dimeric 5-hydroxy-2-hexenoic acid isolated from culture broth of Clonostachys rogersoniana.

Dae-Cheol Choi, Dae-Won Ki, Yoon Hee Kim, Min-Ju Park, Ji-Yul Kim, In-Kyoung Lee, Bong-Sik Yun

Abstract read
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Article in The Journal of antibiotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dae-Cheol ChoiDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan, 54596, Korea.
Dae-Won KiDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan, 54596, Korea.
Yoon Hee KimDepartment of Food and Nutrition, College of Engineering, Daegu University, Gyeongsan, 38453, Republic of Korea.
Min-Ju ParkDepartment of Food and Nutrition, College of Engineering, Daegu University, Gyeongsan, 38453, Republic of Korea.
Ji-Yul KimDepartment of Genetic Resources Research, National Marine Biodiversity Institute of Korea, Seocheon, Republic of Korea.
In-Kyoung LeeDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan, 54596, Korea.
Bong-Sik YunDivision of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Gobong-ro 79, Iksan, 54596, Korea. bsyun@jbnu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new dimeric 5-hydroxy-2-hexenoic acid, clonohexenoic acid (1), a known 14-membered macrolide, acremodiol B (2), and two known benzochromenone derivatives, alternariol (3) and 2-hydroxyalternariol (4), were isolated from a culture broth of Clonostachys rogersoniana. The structures of these isolated compounds were determined using spectroscopic methods. Antimicrobial and cytotoxic activities of these compounds were then assessed. Compounds 1‒4 exhibited antimicrobial activities against Bacillus subtilis and Propionibacterium acnes. In addition, compounds 3 and 4 showed antibacterial activities against B. cereus and cytotoxic activities against three human cancer cell lines, A549, HCT-116, and Mia Paca-2.

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsHypocrealesBacillus cereusBacillus subtilisCell Line, TumorCulture MediaHumansMicrobial Sensitivity TestsMolecular StructurePropionibacterium acnesAnti-Bacterial AgentsAntineoplastic AgentsCulture Media

Identifiers

PMID40275026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.