Evidence map›Paper›PMID 40274749›Full record

ArticleJournal of general internal medicine2026

In Pursuit of Person-Centered Medicine: How Do People with Type 2 Diabetes Choose Glucose-Lowering Medications? A Qualitative Study.

Elizabeth H Golembiewski, Xinyuan Ning, Mindy M Mickelson, Janet P Gockerman, Michael Tesulov, Bertina Labatte, Rozalina G McCoy

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth H GolembiewskiDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. golembiewski.elizabeth@mayo.edu.ORCID 0000-0003-1015-3935
Xinyuan NingDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.
Mindy M MickelsonMayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Rochester, MN, USA.
Janet P Gockerman, Grand Rapids, USA.
Michael Tesulov, Rochester, USA.
Bertina Labatte, Rochester, USA.
Rozalina G McCoyDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.

Funding

Patient-Centered Outcomes Research Institute DB-2020C2-20306
6 · The paper itself

Abstract

backgroundClinical guidelines recommend person-centered selection of glucose-lowering therapies that takes patient goals, preferences, and needs into consideration. However, there is limited understanding of how patients' preferences and experiences shape their medication choices.

objectiveTo explore how individuals with type 2 diabetes (T2D) choose glucose-lowering medications, focusing on their treatment goals, preferences, and alignment between patient and clinician priorities.

designQualitative study.

participantsForty adults with T2D at moderate cardiovascular disease risk, currently taking ≥ 1 glucose-lowering medication, recruited from two health systems in the Midwestern and Southern United States. APPROACH: Semi-structured individual interviews were conducted to explore factors influencing medication choice, quality of communication with clinicians, and degree of patient-perceived alignment between patient and clinician treatment goals. KEY

resultsAmong the 40 participants, 55% were female with a mean age of 56.1 years (SD 13.6). The majority identified as White (50.0%) or Black (37.5%). Participants emphasized the importance of avoiding specific side effects and achieving efficacy in their T2D medication choices. While participants valued clear and comprehensive information about medications from clinicians, many described unmet needs and often supplemented clinical information with advice from peers and online sources. Perceptions around medication decision-making authority varied, with some participants preferring patient-led choices, others relying on clinician expertise, and many advocating for a collaborative or shared decision-making approach to selecting a T2D medication. Discrepancies were noted between clinical priorities and person-centered outcomes, with patients prioritizing quality of life and manageable treatment regimens over strict clinical targets.

conclusionsUnderstanding patient preferences and experiences is crucial for achieving person-centeredness in T2D medication management. Participants described diverse approaches to evaluating glucose-lowering medications, prioritizing quality of life, ease of adherence, and minimizing side effects. Transparent and collaborative communication with clinicians was identified as crucial for aligning treatment plans with patient values.

Indexed as

Diabetes Mellitus, Type 2Hypoglycemic AgentsPatient-Centered CarePatient PreferenceAdultAgedFemaleHumansMaleMiddle AgedPhysician-Patient RelationsQualitative ResearchHypoglycemic Agentsantihyperglycemic medicationspatient-clinician communicationpatient preferencesqualitative researchshared decision-makingtype 2 diabetes

Identifiers

PMID40274749
PMCPMC12894559

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.