Evidence map›Paper›PMID 40274710›Full record

ArticleDermatology and therapy2025

Dupilumab, a Novel Treatment for Peripheral Neuropathy: A Case Series.

Sunny B Patel, David R Roy, Bart W B Sweers, Michael K Coffin

Abstract read
In one paragraph

Article in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sunny B PatelWilliam Carey University College of Osteopathic Medicine, 710 William Carey Parkway, Hattiesburg, MS, 39401, USA. Sunnybpatel89@gmail.com.ORCID http://orcid.org/0000-0002-0247-4416
David R RoyWilliam Carey University College of Osteopathic Medicine, 710 William Carey Parkway, Hattiesburg, MS, 39401, USA.
Bart W B SweersRadboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands.
Michael K CoffinWilliam Carey University College of Osteopathic Medicine, 710 William Carey Parkway, Hattiesburg, MS, 39401, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral neuropathy is a chronic neurological disorder that can present with a multitude of symptoms. It is observed in association with various disease states and organ systems. In the process of treatment for atopic dermatitis, we have observed that patients reported improvements in their previously diagnosed neuropathies, essentially, relief from neuropathic symptoms such as burning, itching, or tingling. On the basis of these observations, we conducted a single-arm trial to survey the qualitative changes in patients with peripheral neuropathy. Ten patients with atopic dermatitis with previously diagnosed peripheral neuropathies were treated with dupilumab (DP) and observed for symptom changes over 6 months. A paired t-test was used to determine whether DP might potentially be used as an off-label treatment for patients with peripheral neuropathy and dermatological conditions. Our patients showed significant symptom relief, thus suggesting that further investigation of the use of DP for patients with neuropathies is warranted.

Indexed as

BiologicalsDupilumabPeripheral neuropathy

Identifiers

PMID40274710
PMCPMC12092312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.