Evidence map›Paper›PMID 40274619›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Natural product-based nanotechnological formulations for colorectal cancer treatment.

Lanfang Wu, Jiali Wu, Xinyu Wang, Youfa Xu, Zhizhe Lin, Jianming Chen, Xin Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lanfang Wu *Fujian University of Traditional Chinese Medicine, No. 1 Qiuyang Road, Fuzhou, 350122, China.
Jiali Wu *Fujian University of Traditional Chinese Medicine, No. 1 Qiuyang Road, Fuzhou, 350122, China.
Xinyu Wang *, Shanghai Wei Er Lab, Shanghai, 201707, China.
Youfa Xu, Shanghai Wei Er Lab, Shanghai, 201707, China.
Zhizhe Lin, Shanghai Wei Er Lab, Shanghai, 201707, China.
Jianming ChenFujian University of Traditional Chinese Medicine, No. 1 Qiuyang Road, Fuzhou, 350122, China. chenjm0711@163.com.
Xin WuFujian University of Traditional Chinese Medicine, No. 1 Qiuyang Road, Fuzhou, 350122, China. wuxin007@126.com.

Funding

Jianming Chen X2019006-Talentsxin wu CYQN2023017xin Wu JJ-QYJS-01-22-0853
6 · The paper itself

Abstract

Colorectal cancer is one of the most common malignancies affecting the gastrointestinal tract. A silent onset often marks it and carries a poor prognosis. Studies have shown that natural products can suppress the growth of colorectal cancer and exert therapeutic effects at the molecular level. However, unfavorable physicochemical properties frequently hinder their clinical application, such as low solubility, limited bioavailability, short half-life, and rapid systemic clearance. As scientific and technological progress continues, increasing attention has been directed toward nanotechnology-based approaches. Techniques involving nanoparticles, liposomes, and micelles are being explored to improve drug delivery. These advancements provide a promising foundation for overcoming the limitations associated with natural products. This review systematically examines the application of nano-formulations for natural ingredients to offer meaningful insights into their. potential use in treating colorectal cancer.

Indexed as

Antineoplastic AgentsBiological ProductsColorectal NeoplasmsAnimalsDrug Delivery SystemsHumansLiposomesNanoparticlesNanotechnologyAntineoplastic AgentsBiological ProductsLiposomesColorectal cancerCombination therapyNanotechnologyNatural productsTargeted therapy

Identifiers

PMID40274619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.