Evidence map›Paper›PMID 40274616›Full record

ArticleCardiovascular and interventional radiology2025

Preoperative Embolization Followed by Tumor Resection Without Time Interval in Advanced Juvenile Nasopharyngeal Angiofibroma.

Yu He, Rujian Hong, Siyu Wang, Jiawei Wu, Wanpeng Li, Huankang Zhang, Kai Xue, Quan Liu, Yurong Gu, Xicai Sun and 5 more

Abstract read
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Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yu He *Department of Radiology, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Rujian Hong *Department of Radiology, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Siyu WangDepartment of Radiology, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Jiawei WuDepartment of Radiology, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Wanpeng LiDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Huankang ZhangDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Kai XueDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Quan LiuDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Yurong GuDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Xicai SunDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Houyong LiDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Yan ShaDepartment of Radiology, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China.
Hongmeng YuDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Dehui WangDepartment of Otolaryngology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.
Qiang LiuDepartment of Radiology, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China. liuqiang.2017@163.com.ORCID http://orcid.org/0000-0003-2586-860X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study explored the feasibility and security of the clinical application of preoperative embolization and tumor resection for advanced juvenile nasopharyngeal angiofibroma (JNA) without a time interval, performed on the same date, and under the same general anesthesia (GA). MATERIALS AND

methodsBetween December 2020 and December 2023, patients with JNA underwent embolization and resection at our hospital. All patients underwent preoperative embolization using liquid embolic material under GA with partial coil assistance; the tumor was removed immediately under the same GA. Both embolization and resection were performed on the same date in the same hybrid operating room without a time interval. Outcome measures included adverse events, blood loss, residual disease, and recurrence.

resultsComplete tumor embolization and complete tumor resection (R0) were achieved in 27 patients under a single GA. 1/27 patient (3.7%) experienced adverse events related to nontarget embolization of the cerebral vessels. However, due to timely detection and treatment, no functional disability occurred after delayed tumor resection and active treatment for cerebral infarction. During a mean follow-up of 12 months, 25/27 patients (92.6%) had no residual tumor seen on imaging or endoscopic evaluation, while residual tumor was observed in 2/27 patients (7.4%). No further treatments were performed. The mean blood loss in tumor resection was 911 mL (100-3400 mL).

conclusionNo interval between preoperative embolization and tumor resection is a feasible and safe treatment modality in patients with advanced JNA.

Indexed as

AngiofibromaEmbolization, TherapeuticNasopharyngeal NeoplasmsAdolescentBlood Loss, SurgicalChildChild, PreschoolFeasibility StudiesFemaleHumansMalePreoperative CareRetrospective StudiesTime FactorsTreatment OutcomeEndoscopic resectionJuvenile nasopharyngeal angiofibromaNo time intervalPreoperative embolization

Identifiers

PMID40274616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.