Evidence map›Paper›PMID 40274553›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2025

[Research progress on the role of invariant natural killer T cells in immune-mediated liver injury].

L X Bai, W K Hao, J R Li, S F Li, L T Zhang, J F Li

Abstract readReviewEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

L X BaiThe First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China.
W K HaoThe First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China.
J R LiThe First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China.
S F LiThe First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China.
L T ZhangThe First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China Institute of Portal Hypertension, the First Hospital of Lanzhou University, Lanzhou 730000, China.
J F LiThe First Clinical College of Medicine, Lanzhou University, Lanzhou 730000, China Department of Hepatology, the First Hospital of Lanzhou University, Lanzhou 730000, China.

Funding

Joint Scientific Research Fund of Gansu Province 23JRRA1489, 24JRRA911Medical Education Innovation and Development Project of Lanzhou University lzuyxcx-2022-213, lzuyxcx-2022-131, lzuyxcx-2022-147National Innovation and Entrepreneurship Training Program for College Students 202410730191National Natural Science Foundation of China 82360132
6 · The paper itself

Abstract

The pathogenesis of immune-mediated liver injury is related to immune regulation disorders. In recent years, researchers have focused on the unique role of invariant natural killer T cells (iNKT cells) in immune-mediated liver injury. iNKT cells, a special subset of lymphocytes, are crucial for immune regulation by bridging innate and adaptive immunity. iNKT cells interact with various immune cells and possess strong immune regulatory capabilities, but their role is complex, potentially promoting liver injury or protecting the liver from damage. This article reviews the latest research progress on iNKT cells in immune-mediated liver injury and describes some factors that regulate immune liver injury by altering the expression of glycosphingolipids, such as liver X receptor and tumor progression site2. In addition, the research results are explored to assist in deepening the understanding of the mechanism of immune-mediated liver injury so as to provide new directions for the development of related treatment strategies.

Indexed as

LiverLiver DiseasesNatural Killer T-CellsAnimalsHumans

Identifiers

PMID40274553
PMCPMC12899218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.