Evidence map›Paper›PMID 40274409›Full record

ArticleThorax2025

Future risk projection to engage 'near-miss' individuals in lung cancer screening eligibility: an analysis of ILST data.

Chellan Kumarasamy, Kim Betts, Richard Norman, Annette McWilliams, Emily Stone, David C L Lam, Renee Manser, Paul Fogarty, Henry M Marshall, Stephen Lam and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Thorax, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chellan KumarasamyCurtin Medical School, Curtin University, Perth, Western Australia, Australia.ORCID 0000-0001-7775-3578
Kim BettsCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Richard NormanCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Annette McWilliamsDepartment of Respiratory Medicine, Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
Emily StoneDepartment of Thoracic Medicine and Lung Transplantation, St Vincent's Hospital Sydney, Sydney, New South Wales, Australia.
David C L LamUniversity of Hong Kong Faculty of Medicine, Hong Kong, Hong Kong.
Renee ManserDepartment of Respiratory Medicine, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Paul FogartyInternal Medicine Clinical Institute, Epworth HealthCare, Richmond, Victoria, Australia.
Henry M MarshallUniversity of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane, Queensland, Australia.ORCID 0000-0002-9626-8014
Stephen LamBritish Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
Martin TammemagiDepartment of Health Sciences, Brock University-St. Catharines Campus, St. Catharines, Ontario, Canada.
Kwun M FongUniversity of Queensland Thoracic Research Centre, The Prince Charles Hospital, Brisbane, Queensland, Australia.
Sukhinder Atkar-KhattraIntegrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.
Fraser BrimsCurtin Medical School, Curtin University, Perth, Western Australia, Australia fraser.brims@curtin.edu.au.ORCID 0000-0002-6725-7535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLung cancer risk increases with time, and participants who are initially ineligible for lung cancer screening (LCS) could become eligible later. The aim of this study was to determine the proportion of people (initially ineligible) who may become eligible in a risk model-based LCS programme and the impact smoking cessation could have on this cohort.

methodsAll potential participants for the International Lung Screening Trial aged 55-80 years, ineligible for Low-dose CT screening at baseline (PLCO

results4451 subjects with a median age of 61 (IQR: 57-66) years were included. Assuming no change in smoking status post evaluation, 2239 participants (50.3%) became eligible (PLCO

conclusionsFuture risk projection of eligibility could provide a time window for reassessment of risk on an individual level. It is important to provide smoking cessation services to individuals who are ineligible for LCS at the initial programme contact.

Indexed as

Early Detection of CancerLung NeoplasmsAgedAged, 80 and overFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsSmokingSmoking CessationTomography, X-Ray ComputedClinical EpidemiologyLung CancerSmoking cessation

Identifiers

PMID40274409
PMCPMC12322426

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.