Evidence map›Paper›PMID 40274227›Full record

ArticleJournal of advanced research2026

miR398-SlCSD1 module participates in the SA-H

Xiujuan Wang, Xinshan Zhang, Yuanyuan Liu, Lei Ru, Guochao Yan, Yunmin Xu, Youjian Yu, Zhujun Zhu, Yong He

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bioinformatics Analysis of the TomatoPlants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiujuan WangCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China.
Xinshan ZhangCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China.
Yuanyuan LiuCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China.
Lei RuCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China.
Guochao YanCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China.
Yunmin XuCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China.
Youjian YuCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China.
Zhujun ZhuCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China. Electronic address: zhuzj@zafu.edu.cn.
Yong HeCollege of Horticulture Science, Zhejiang A&F University, Hangzhou 311300 Zhejiang, China; Key Laboratory of Quality and Safety Control for Subtropical Fruit and Vegetable of Ministry of Agriculture and Rural Affairs, Hangzhou 311300 Zhejiang, China. Electronic address: heyong@zafu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSalicylic acid (SA) is essential for immune response signal transduction in higher plants, with its signaling thought to be enhanced through interactions with reactive oxygen species (ROS). However, the exact mechanisms behind this SA self-amplifying signaling are still not well understood.

objectivesIn this study, we report the involvement of the miR398b-SlCSD1 module in the SA-H

methodsExperiments were conducted using various concentrations of SA to assess its impact on ROS metabolism and the expression of SlCSD1 and sly-miR398. CRISPR/Cas9 was employed to knock out sly-miR398 and SlCSD1. Bioinformatics analyses, dual-luciferase reporter assays (Dual-Luc), and electrophoretic mobility shift assays (EMSA) were used to identify SA-responsive transcription factors and validate their regulation of sly-miR398b. The role of miR398 in endogenous SA synthesis was examined using overexpression and knockout tomato lines.

resultsLow SA concentrations stimulated H

conclusionTaken together, our results shed light on the involvement of the miR398-SlCSD1 module in the SA-H

Indexed as

Hydrogen PeroxideMicroRNAsPlant ProteinsSalicylic AcidSolanum lycopersicumCRISPR-Cas SystemsFeedback, PhysiologicalGene Expression Regulation, PlantPlants, Genetically ModifiedReactive Oxygen SpeciesSignal TransductionHydrogen PeroxideMicroRNAsPlant ProteinsReactive Oxygen SpeciesSalicylic AcidH(2)O(2)miR398Reactive oxygen speciesSalicylic acidTomato

Identifiers

PMID40274227
PMCPMC12869259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.