Evidence map›Paper›PMID 40273556›Full record

ArticleEnvironment international2025

Sex differences in the association between long-term ambient particulate air pollution and the intestinal microbiome composition of children.

Thessa Van Pee, Liesa Engelen, Marthe De Boevre, Muriel Derrien, Janneke Hogervorst, Roger Pero-Gascon, Michelle Plusquin, Giulia Poma, Arnau Vich I Vila, Adrian Covaci and 4 more

Abstract read
In one paragraph

Article in Environment international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thessa Van PeeCentre for Environmental Sciences, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Liesa EngelenCentre for Environmental Sciences, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Marthe De BoevreCentre of Excellence in Mycotoxicology and Public Health, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.
Muriel DerrienLaboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, Katholieke Universiteit Leuven 3000 Leuven, Belgium.
Janneke HogervorstCentre for Environmental Sciences, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Roger Pero-GasconCentre of Excellence in Mycotoxicology and Public Health, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium.
Michelle PlusquinCentre for Environmental Sciences, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Giulia PomaToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Arnau Vich I VilaLaboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, Katholieke Universiteit Leuven 3000 Leuven, Belgium.
Adrian CovaciToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Lynn VanhaeckeLaboratory of Integrative Metabolomics (LIMET), Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Sarah De SaegerCentre of Excellence in Mycotoxicology and Public Health, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium; Department of Biotechnology and Food Technology, Faculty of Sciences, University of Johannesburg, South Africa.
Jeroen RaesLaboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, Katholieke Universiteit Leuven 3000 Leuven, Belgium.
Tim S NawrotCentre for Environmental Sciences, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium; Department of Public Health and Primary Care, Leuven University, Herestraat 49-box 706, 3000 Leuven, Belgium. Electronic address: tim.nawrot@uhasselt.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiome is essential for gastrointestinal and overall health, yet its response to air pollution in children remains underexplored. In a study involving 412 young children from the ENVIRONAGE cohort, stool samples were analysed via Illumina Miseq sequencing to assess microbiome alpha diversity (observed richness, species evenness, and Shannon diversity) and composition. Exposure to previous year particulate air pollution (black carbon, PM

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureGastrointestinal MicrobiomeParticulate MatterChildChild, PreschoolFecesFemaleHumansMaleSex FactorsAir PollutantsParticulate MatterAir pollutionAlpha diversityIntestinal microbiomeParticulate

Identifiers

PMID40273556
PMCPMC12086174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.