Evidence map›Paper›PMID 40273493›Full record

ArticleClinics (Sao Paulo, Brazil)2025

Cost-consequence analysis of surgical and clinical treatment modalities of laryngeal cancer.

Alexandre Bezerra Dos Santos, Patrícia Coelho de Soárez, Rossana Veronica Mendoza Lopez, Luciana Martins Rozman, Alessandro Gonçalves Campolina

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexandre Bezerra Dos SantosDepartamento de Cirurgia de Cabeça e Pescoço, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Patrícia Coelho de SoárezDepartamento de Medicina Preventiva, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Rossana Veronica Mendoza LopezCentro de Investigação Translacional em Oncologia, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Luciana Martins RozmanDepartamento de Medicina Preventiva, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
Alessandro Gonçalves CampolinaCentro de Investigação Translacional em Oncologia, Instituto do Câncer do Estado de São Paulo, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil. Electronic address: alessandro.campolina@hc.fm.usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaryngeal Squamous Cell Carcinoma (LSCC) may be treated clinically or surgically as a therapeutic option with a curative intention. The aim of this study is to compare direct medical costs and overall survival associated with the treatment of LSCC.

methodsRetrospective cost-consequence analysis, from the perspective of a Brazilian public hospital that included patients with LSCC, from 2014 to 2017. Unit costs were estimated using a macro-costing approach. The Propensity Score Matching method was used. Survival analyses were performed using the Kaplan-Meier method.

resultsThe therapeutic modalities were similar in terms of total costs: USD 32,259.65 for the clinical group and USD 34,385.87 for the surgical group (p = 0.215). Patients in the surgical group showed better overall survival than the clinical group (HR 0.53; p = 0.047).

conclusionBoth therapeutic modalities for the treatment of LSCC showed similar total costs. Nevertheless, overall survival was better in the surgical group.

Indexed as

Carcinoma, Squamous CellHealth Care CostsLaryngeal NeoplasmsAdultAgedBrazilCost-Benefit AnalysisFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPropensity ScoreRetrospective StudiesSurvival AnalysisCost analysisCostsLaryngeal neoplasmsOropharyngeal neoplasms

Identifiers

PMID40273493
PMCPMC12051698

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.