Evidence map›Paper›PMID 40273492›Full record

ArticleClinics (Sao Paulo, Brazil)2025

Cost-effectiveness of selective laser trabeculoplasty as a replacement for hypotensive eye drops in the Brazilian public health system.

Leopoldo Ernesto Oiticica Barbosa, Wilma Lelis Barboza, Ricardo Agusto Paletta Guedes, Alfredo Chaoubah, Marcelo Hatanaka

Abstract read
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leopoldo Ernesto Oiticica BarbosaUniversidade de São Paulo, São Paulo, SP, Brazil; Instituto de Olhos de Maceió, Farol, Maceió, AL, Brazil. Electronic address: leopoldo.barbosa@fm.usp.br.
Wilma Lelis BarbozaUniversidade de São Paulo, São Paulo, SP, Brazil.
Ricardo Agusto Paletta GuedesUniversidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.
Alfredo ChaoubahUniversidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.
Marcelo HatanakaUniversidade de São Paulo, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to determine the cost-effectiveness of selective laser trabeculoplasty (SLT) as a replacement for hypotensive eye drops in the Brazilian Unified Health System (SUS).

methodsThe authors conducted a cost-effectiveness economic assessment using data from a previously published prospective, non-randomized, single-arm interventional study. The costs were estimated from the perspective of the SUS, using data from the SIGTAP. The authors proposed a value of R$ 588.00 for bilateral SLT, based on the observed cost reduction with medications in the SLT group. Effectiveness was assessed as a reduction in intraocular pressure (IOP).

resultsThe average annual cost of medications per patient was R$ 669.53 in the reference group (continuous use of eye drops) and R$ 80.62 in the intervention group (SLT). The average IOP reduction was 9.3 mmHg in the reference group and 9.8 mmHg in the intervention group. SLT proved to be a dominant strategy compared to the continuous use of eye drops, presenting a greater reduction in IOP and a lower total annual cost. The incremental cost-effectiveness ratio (ICER) was negative (-R$ 1.82), indicating that SLT is more effective and less costly.

conclusionsSLT is a cost-effective alternative to hypotensive eye drops in the treatment of glaucoma in the SUS. The adoption of SLT can optimize resource allocation and improve clinical outcomes for patients with glaucoma. Implementing SLT at the proposed procedural cost optimizes spending by substantially reducing long-term medication costs and offering a sustainable alternative within the healthcare system.

Indexed as

Antihypertensive AgentsGlaucomaLaser TherapyOphthalmic SolutionsTrabeculectomyBrazilCost-Benefit AnalysisFemaleHumansIntraocular PressureMaleMiddle AgedNational Health ProgramsProspective StudiesTreatment OutcomeAntihypertensive AgentsOphthalmic SolutionsCost-effectivenessEye dropsGlaucomaIntraocular pressure

Identifiers

PMID40273492
PMCPMC12051510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.