ArticlePloS one2025
Determinants of pelvic organ prolapse among adult gynecologic patients in Mekelle University Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia: Case control study design.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPelvic organ prolapse is a major cause of morbidity among women in both high-income and low-income countries. Despite the severity of the problem, the risk factors associated with pelvic organ prolapse has been poorly understood in Ethiopia mainly in the study area. Hence, the purpose of this study was to identify determinants of pelvic organ prolapse among adult gynecologic patients at Mekelle University Ayder Comprehensive Specialized Hospital.
objectiveTo identify determinants of pelvic organ prolapse among adult gynecologic patients in Mekelle University Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia, 2024.
methodsHospital-based case-control study design was conducted from March 01, 2024 to May 30, 2024. All cases diagnosed with pelvic organ prolapse were enrolled in the study. Then, 4:1 control-to-cases ratio was applied. Data were entered into Epi Data version 4.6 and analyzed using SPSS version 21. Figures and tables were used for descriptive statistics. Variables with P-value less than 0.2 during binary logistic regression were labeled as candidates for multivariable logistic regression to identify independent predictors of pelvic organ prolapse at p-value < 0.05. The overall model fitness was checked by Hosmer Lemeshow at a P-value > 0.05. Finally, variables with P-value less than 0.05 and a 95% confidence interval of adjusted odds ratio were considered significant factors for the determinants of pelvic organ prolapse.
resultsA total of 478 participants were recruited with a 100% response rate for both cases and controls. Low income (AOR=3.3; 95% CI: 1.1-9.7), vaginal tear (AOR=6.6; 95% CI: 2.5-17.6), menopausal status (AOR=9.2, 95% CI:2.3-37.4), body mass index <18 kg/m2 (AOR=6.3, 95% CI: 2.7-14.4), body mass index ≥25 (AOR= 5.6, 95% CI: 1.5-21.2) and chronic constipation (AOR=6.4, 95% CI: 2.9-13.9) were identified as determinants of pelvic organ prolapse.
conclusionsIn this study, income of the participant, vaginal tear, menopausal status, body mass index (both underweight and overweight), and chronic constipation were factors found to be significantly associated with pelvic organ prolapse. Therefore, creating awareness about risk factors of pelvic organ prolapse, screening and early intervention, weight management program, and hormonal support is recommended.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.