ReviewChemistry & biodiversity2025
Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review.
Review in Chemistry & biodiversity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its promising biotechnological potential and justifying the development of research in species that remain unstudied; additionally, it presents new perspectives based on the current knowledge, including the study of in vitro cultures and co-cultures of the members of this subfamily as a sustainable approach to standardizing their chemical profiles and, consequently, enhancing their biotechnological potential. The information was collected from scientific databases such as Wiley Online Library, PubMed, Springer Link, Scielo, and Nature Research for 4 years. Verification of the scientific names and affiliations of the plants was carried out using the databases Global Biodiversity Information Facility (www.gbif.org), Plants of the World Online (www.plantsoftheworldonline.org), and The Plant List (www.theplantlist.org). To date, 512 chemical compounds have been reported for this subfamily, evidencing a wide diversity of chemical structures. It was also shown that the extracts, fractions, isolated pure compounds, and nanoparticles of this subfamily present antimicrobial, antioxidant, anticancer, anti-inflammatory, antidiabetic, and antihyperglycemic activity, among others. Likewise, it is evident that the members of this subfamily do not present toxicity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.