SynthesisNutrition reviews2025
Community-Based Child Food Interventions/Supplements for the Prevention of Wasting in Children Up to 5 Years at Risk of Wasting and Nutritional Oedema: A Systematic Review and Meta-Analysis.
Synthesis in Nutrition reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Association of dietary diversity with anaemia among children (6 mo-9 y) in Puducherry, South India: A cross-sectional study.The Indian journal of medical research · 2026Article
- Maternal nutrition practices and its implications for child growth and development in Jimma Town a community based cross sectional study.Scientific reports · 2026Article
- Acceptability, feasibility and equity implications of nutritional supplementation interventions for the prevention of wasting in infants and young children: A rapid qualitative evidence synthesis.African journal of primary health care & family medicine · 2026Review
- Machine learning-based prediction of fever among under-five children in Ethiopia: A national-level study.PloS one · 2026Article
- Prevention of wasting and nutritional oedema: evidence gaps identified during WHO guideline development.BMJ global health · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
contextMalnutrition poses a significant threat to child health, with millions of children worldwide affected by wasting, which increases the risk of morbidity and mortality.
objectiveIn this study we sought to evaluate the effectiveness of community-based infant/child food interventions and supplements for preventing wasting among children up to 5 years at risk of wasting and nutritional oedema. The World Health Organization commissioned this review to update their guidelines on wasting due to malnutrition in children. DATA SOURCES: Nine databases were searched from inception until July 2021 and an updated search was carried out on MEDLINE and Ovid MEDLINE until April 13, 2023, and included 24 studies (98 articles) evaluating the impact of community-based infant/child food interventions/supplements for the prevention of wasting among children up to 5 years. DATA EXTRACTION: Two review authors independently extracted data and assessed the quality of included studies using the Cochrane Risk of Bias Tool 2.0. Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) criteria were used to assess the quality of evidence. DATA ANALYSIS: This review included 19 cluster-randomized controlled trials (cRCTs) and 5 RCTs evaluating the impact of community-based infant/child food interventions/supplements including fortified blended foods (FBFs), small-quantity (SQ), medium-quantity (MQ), or large-quantity (LQ) lipid-based nutrient supplements (LNS), and multiple micronutrient powder (MNP) for the prevention of wasting among children up to 5 years of age. The analysis showed that infants/children given supplementation with LNS (either SQ, MQ, or LQ) had significantly reduced wasting and significant improvements in weight-for-age z-score, mid-upper-arm circumference (MUAC), and underweight prevalence, along with significant reductions in mortality. The MNP supplementation had little or no impact on wasting but was associated with increased incidences of rapid breathing/chest indrawing and diarrhea morbidity. Overall, the studies were judged to have raised some concerns for the outcomes of wasting and adverse anthropometric indices. However, the GRADE analysis suggested low-to-moderate certainty of outcomes.
conclusionsThe findings of this review highlight the effectiveness of SQ-LNS and MQ/LQ-LNS supplementation in decreasing rates of wasting, underweight, and mortality and increasing MUAC and weight-for-age z-scores. Methodological limitations in most studies emphasize the need for future trials with direct comparisons of various dietary supplementation strategies. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration number CRD42021277429.
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