Evidence map›Paper›PMID 40272767›Full record

ArticleMolecular neurobiology2025

Inhibition of FOXD3 O-GlcNAc Modification Ameliorates Spinal Cord Injury by Promoting STUB1-Mediated Ubiquitination Degradation of HMGB1.

Wu Zhou, Bo Hei, Yihao Liu, Chengyun Wang, Chunliang Wang, Zihan Ding

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wu ZhouDepartment of Neurosurgery, the 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwai Street, Nanchang, 330006, Jiangxi, China.
Bo HeiDepartment of Neurosurgery, Peking University People's Hospital, Peking University, No.11 Xizhimen South Street, Beijing, Beijing, 100044, China.
Yihao LiuDepartment of Neurosurgery, the 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwai Street, Nanchang, 330006, Jiangxi, China.
Chengyun WangDepartment of Neurosurgery, the 2nd Affiliated Hospital, Jiangxi Medical College, Nanchang University, 1 Minde Street, Nanchang, 330006, Jiangxi, China.
Chunliang WangDepartment of Neurosurgery, the 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwai Street, Nanchang, 330006, Jiangxi, China. wangchunliang@ncu.edu.cn.
Zihan DingDepartment of Trauma and Acute Care Surgery, the 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwai Street, Nanchang, 330006, Jiangxi, China. dzh1221@email.ncu.edu.cn.

Funding

National Natural Science Foundation of China 82260525
6 · The paper itself

Abstract

Spinal cord injury (SCI) is a serious complication of spinal fractures and/or dislocations, characterized by sensory and motor dysfunction in the trunk and limbs. The pathogenesis of SCI is highly complex and remains poorly understood. The role of O-GlcNAc modification and FOXD3 in SCI was studied in this study. The cell and animal models of SCI were established by H

Indexed as

AcetylglucosamineForkhead Transcription FactorsHMGB1 ProteinProteolysisSpinal Cord InjuriesUbiquitinationUbiquitin-Protein LigasesAnimalsApoptosisHydrogen PeroxideMaleOxidative StressPC12 CellsRatsRats, Sprague-DawleyAcetylglucosamineForkhead Transcription FactorsHMGB1 ProteinHydrogen PeroxideUbiquitin-Protein LigasesFOXD3HMGB1O-GlcNAcSpinal cord injurySTUB1

Identifiers

PMID40272767

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.