Evidence map›Paper›PMID 40272748›Full record

ArticleCerebellum (London, England)2025

Mapping Anatomical Landmarks of the Cerebellum Central Core: Enhancing Precision in Surgical Interventions for Cerebellar Lesions.

Luis Gustavo Biondi-Soares, Richard Gonzalo Párraga, Rene Alejandro Apaza-Tintaya, Lucca B Palavani, Veronica Alzate-Carvajal, Felipe Salvagni, Alexander Feliciano Vilcahuaman Paitán, Gabriel Ataide Monção, Luis Ángel Canache Jiménez, Raphael Wuo-Silva and 1 more

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Article in Cerebellum (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Luis Gustavo Biondi-SoaresDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil.
Richard Gonzalo PárragaDepartment of Neurological Surgery, Neurosurgery Institute of Bolivia, Cochabamba, Bolivia.
Rene Alejandro Apaza-TintayaDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil.
Lucca B PalavaniDepartment of Medicine, Centro Universitario Max Planck, Indaiatuba, Brazil.
Veronica Alzate-CarvajalDepartment of Neurosurgery, Hospital Universitario Fundación Valle de Lili, Cali, Colombia.
Felipe SalvagniDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil.
Alexander Feliciano Vilcahuaman PaitánDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil.
Gabriel Ataide MonçãoDepartment of Neurosurgery, Universidade Estadual de Montes Claros, Montes Claros, MG, Brazil.
Luis Ángel Canache JiménezDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil.
Raphael Wuo-SilvaDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil.
Feres Chaddad-NetoDepartment of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Napoleão de Barros, 715, 6 Th Floor, São Paulo, SP, 04024 - 001, Brazil. fereschaddad@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Similar to the cerebrum, the cerebellum exhibits a central neuronal core region enveloped by a network of white fibers, identified as the central nucleus. The dentate nucleus and the extension of its fibers into the superior cerebellar peduncle play a key role. Understanding this anatomical and functional concept would improve the accuracy of surgical interventions for cerebellar infiltrative lesions. Twenty-two formalin-fixed and frozen human cerebellar and brainstems were stored at -16º C for two weeks, according to the Klingler protocol. Dissection was performed to identify the cerebellar central nucleus and its structures. Images were captured, analyzed, and processed for the distribution of landmarks in each dissection phase. We defined the cerebellar landmarks proximal to the central nucleus. The anatomical division into planes: Superoinferior; we found the superior border of the amygdala and the MCP. Superior: the anterior portion of the horizontal fissure, the MCP, and the origin of the V cranial nerve. Anteroposterior plane: the cerebello-mesencephalic fissure and the postclival fissure. In the medio-lateral plane, we identify the cerebellar vermis's PCS and lateral border. Laterally, the fibers of the MCP and the lateral aspect of the tonsil. The biventral lobule may obscure this landmark, and we consider it an alternative landmark. This study provides reliable anatomical landmarks of the cerebellum, which describe the central cerebellar nucleus. Establishing these landmarks favors three-dimensional knowledge and helps avoid associated neurological damage in this crucial structure.

Indexed as

Anatomic LandmarksCerebellumAgedFemaleHumansMaleMiddle AgedAnatomical landmarksCerebellar central coreCerebellumLandmarksPosterior fossa

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.