Evidence map›Paper›PMID 40272541›Full record

ArticleEuropean child & adolescent psychiatry2025

The use of atypical antipsychotic medications in the treatment of children and adolescents with avoidant/restrictive food intake disorder.

Mariela Mosheva, Yaron Sela, Shani Arad-Rubinshtein, Yaffa Serur, Ganit Omer, Nimrod Hertz-Palmor, Doron Gothelf, Daniel Stein

Abstract read
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Article in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Mariela MoshevaChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel. marymoshev@gmail.com.
Yaron SelaThe Research Center for Internet Psychology, Reichman University, Herzliya, Israel.
Shani Arad-RubinshteinChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel.
Yaffa SerurChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel.
Ganit OmerChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel.
Nimrod Hertz-PalmorChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel.
Doron GothelfChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel.
Daniel SteinChild Psychiatry Division, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 5262000, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAvoidant restrictive food intake disorder (ARFID) is a childhood feeding and eating disorder often associated with marked physical and psychosocial impairment.

objectiveWe assessed the use of atypical antipsychotic (AAP) medications (mostly risperidone) in promoting weight and height gain in children with ARFID.

methodsThe computerized medical records of 21 children with ARFID receiving AAPs in one center in Israel were retrospectively reviewed. Fourteen children received AAPs after 6.30 ± 0.75 months of no weight gain with treatment as usual (either group or individual cognitive behavioral therapy); seven children were admitted to our clinic receiving AAPs in previous facilities because of lack of weight gain. All were followed-up for 18 months. Weight and height were extracted from the medial records at eight time points.

resultsA significant increase was found in weight, height, and body mass index (BMI) over 18 months of treatment with AAPs (Δweight: 9.66 ± 9.24 kg, p < 0.001; Δheight: 10.23 ± 11.54 cm, p < 0.001; ΔBMI = 2.55 ± 1.53 kg/m

conclusionThe addition of AAPs for a period of 18 months may be safe and effective in increasing weight and height in children with ARFID.

Indexed as

Antipsychotic AgentsAvoidant Restrictive Food Intake DisorderRisperidoneWeight GainAdolescentBody HeightBody Mass IndexBody WeightChildCognitive Behavioral TherapyFemaleHumansIsraelMaleRetrospective StudiesTreatment OutcomeAntipsychotic AgentsRisperidoneARFIDAtypical antipsychotic medicationsBody mass indexHeightWeight

Identifiers

PMID40272541
PMCPMC12592295

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