Evidence map›Paper›PMID 40272510›Full record

ArticleEuropean journal of pediatrics2025

Cannabinoid exposure in infants and children in the pediatric emergency department-the child protection perspective.

Dvora Fridler, Lea Ohana Sarna Cahan, Adi Bracha Moshe, Noa Guzner, Itai Gross, Saar Hashavya

Abstract read
In one paragraph

Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dvora FridlerDepartment of Pediatric Emergency Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. dvorafridler@gmail.com.
Lea Ohana Sarna CahanDepartment of Pediatric Emergency Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Adi Bracha MosheDepartment of Pediatric Emergency Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Noa GuznerDepartment of Pediatrics, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Itai GrossDepartment of Pediatric Emergency Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Saar HashavyaDepartment of Pediatric Emergency Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabinoid exposure in pediatric populations has become an increasing concern with the growing legalization and availability of cannabis products. While studies have addressed the clinical presentation of intoxication, limited data exist on child protection team (CPT) activation and child safety concerns in these cases. A 10-year retrospective study (2010-2021) was conducted at Hadassah Medical Center who operates two campuses within the Jerusalem metropolitan area. Cases of children aged 0-48 months with positive urine toxicology for cannabis were analyzed. Data collected included demographics, clinical presentation, and involvement of CPT, child protection services, and police. Out of 36 cases, 29 met the inclusion criteria. The majority (65.5%) were male, with a median age of 14 months. Neurological symptoms were universal, and CPT was activated in all cases (100%). Police reports were filed in 93.1%, while child protection services were contacted in 62.1%. Despite positive drug screens, only one caregiver admitted to cannabis exposure, and more than 60% denied any knowledge of exposure. Most children had no prior reports with social services; however, 11 (37.9%) had multiple pediatric emergency department (PED) visits, suggesting a heightened risk of neglect.

conclusionsCannabis intoxication in young children presents diagnostic challenges due to non-specific symptoms and low caregiver disclosure rates, often leading to unnecessary investigations. Although prior reports of abuse or neglect are uncommon, frequent PED visits may signal neglect. Early CPT involvement is essential in managing these cases and ensuring child safety. WHAT IS KNOWN: • Pediatric cannabis intoxication presents primarily with non-specific neurological symptoms, making early diagnosis challenging. • Most existing studies focus on the clinical aspects of intoxication, with limited data on child protection team involvement and reporting practices. WHAT IS NEW: • Universal involvement of the Child Protection Team (CPT) led to high reporting rates to authorities, with nearly all cases being reported either to the police or to Child Protection Services. • Multiple pediatric emergency department visits, especially for injuries, may indicate neglect even when prior CPS reports are absent.

Indexed as

CannabinoidsChild Protective ServicesEmergency Service, HospitalChild, PreschoolFemaleHumansInfantInfant, NewbornIsraelMaleRetrospective StudiesCannabinoidsCannabinoid exposureCannabis intoxicationChild protectionChild protection team (CPT)Pediatric emergency departmentUrine toxicology

Identifiers

PMID40272510
PMCPMC12021702

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.