Evidence map›Paper›PMID 40272498›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Lena M Unterrainer, Hans P Schmid, Sophie C Kunte, Adrien Holzgreve, Johannes Toms, Paula Menold, Clemens C Cyran, Alexander Karl, Stephan Tschirdewahn, Stephan T Ledderose and 7 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Lena M Unterrainer *Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Hans P Schmid *Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany. Hans.Schmid@med.uni-muenchen.de.ORCID 0009-0002-1259-358X
Sophie C KunteDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Adrien HolzgreveDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Johannes TomsDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Paula MenoldDepartment of Urology, Krankenhaus Barmherzige Brüder, Munich, Germany.
Clemens C CyranDepartment of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.
Alexander KarlDepartment of Urology, Krankenhaus Barmherzige Brüder, Munich, Germany.
Stephan TschirdewahnDepartment of Urology, Klinikum Kempten, Kempten, Germany.
Stephan T LedderoseBavarian Cancer Research Center (BZKF), Partner Site Munich, Munich, Germany.
Lennert EismannDepartment of Urology, LMU University Hospital, LMU Munich, Munich, Germany.
Alexander J TamalunasDepartment of Urology, LMU University Hospital, LMU Munich, Munich, Germany.
Maximilian ScheifeleDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Christian G StiefDepartment of Urology, LMU University Hospital, LMU Munich, Munich, Germany.
Marcus UnterrainerDepartment of Nuclear Medicine, LMU University Hospital, LMU Munich, Marchioninistrasse 15, 81377, Munich, Germany.
Jozefina CasuscelliDepartment of Urology, LMU University Hospital, LMU Munich, Munich, Germany.
Gerald B SchulzDepartment of Urology, LMU University Hospital, LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo determine the best therapeutic strategy for muscle-invasive bladder cancer (BC), the accuracy of lymph node staging is of paramount importance. However, diagnostic performance of conventional computed tomography in BC prior to radical cystectomy (RC) remains unsatisfactory. There is an increased interest in evaluating

methodsFifty-one patients underwent FAPI PET/CT with either [

results20/123 (16.3%) lymph node regions showed UC lymph node metastases. Histopathologically positive lymph nodes were associated with a significantly higher FAPI uptake compared to negative lymph nodes regarding SUV

conclusionOverall, FAPI PET imaging shows a significantly higher sensitivity than CT analysis for detection of locoregional lymph node metastases in UC. [

Indexed as

CystectomyPositron Emission Tomography Computed TomographyUrinary Bladder NeoplasmsAgedAged, 80 and overFemaleGallium IsotopesGallium RadioisotopesHumansLymphatic MetastasisMaleMiddle AgedQuinolines68Ga-FAPIGallium IsotopesGallium RadioisotopesQuinolinesF-18 FAPIFAPI PETGa-68 FAPIUrothelial carcinoma

Identifiers

PMID40272498
PMCPMC12397140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.