ArticleEuropean radiology2025
Reduction of biopsy rate in BI-RADS4 breast lesions: potential of an abbreviated advanced DWI protocol.
Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- 40 Years of diffusion MRI in the brain: From history to emerging frontiers.Imaging neuroscience (Cambridge, Mass.) · 2026Review
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4 authors.
Funding
Abstract
objectivesThis study compared the diagnostic performance of diffusion biomarkers estimated from an abbreviated diffusion-weighted imaging (DWI) protocol and assessed their potential to reduce unnecessary biopsies of benign BI-RADS 4 lesions identified on dynamic contrast-enhanced (DCE) MRI.
methodsA retrospective study was conducted from 2019 to 2023. All patients underwent abbreviated DWI at 3 T with four b-values (0 s/mm
resultsIn total, 168 female patients (mean age ± standard deviation, 56.2 ± 13.5 years) with 178 BI-RADS 4 lesions on DCE MRI were analyzed. The median ADC
conclusionDiffusion MRI biomarkers obtained using an abbreviated DWI protocol reduced unnecessary biopsies in BI-RADS 4 lesions, with K performing slightly better than ADC. KEY POINTS: Question MRI BI-RADS category 4 includes a substantial number of benign lesions, and reducing unnecessary biopsies remains a critical clinical concern. Findings The parameters from abbreviated DWI show lesion differentiation comparable to ADC and have greater potential to reduce unnecessary biopsies. Clinical relevance This study underscores the potential of imaging biomarkers from abbreviated DWI for assessing breast MRI BI-RADS 4 lesions. These biomarkers may be comparable or superior to standard ADC in reducing unnecessary biopsies and could aid in improving patient management decisions.
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