Evidence map›Paper›PMID 40272470›Full record

ReviewInnere Medizin (Heidelberg, Germany)2025

[Rare diseases: the role of internal medicine].

Tilman Sauerbruch, Stefan Aretz, Helge Hebestreit, Harald Kaemmerer, Lutz Nährlich, Britta Siegmund, Georg Ertl, Deutsche Gesellschaft für Innere Medizin (DGIM)

Abstract readEnglish AbstractReview
In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Rare diseases: a concept for a structured diagnostic pathway].Innere Medizin (Heidelberg, Germany) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tilman SauerbruchMedizinische Klinik I, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.
Stefan AretzInstitut für Humangenetik, Zentrum für erbliche Tumorerkrankungen, Biomedizinisches Zentrum, Universitätsklinikum Bonn AöR, Venusberg-Campus 1, Bonn, Deutschland.
Helge HebestreitUniversitätsklinikum Würzburg, Würzburg, Deutschland.
Harald KaemmererDeutsches Herzzentrum München, Klinikum der Technischen Universität München, München, Deutschland.
Lutz NährlichZentrum für Kinderheilkunde und Jugendmedizin, Abteilung Allgemeine Pädiatrie und Neonatologie, Funktionsbereich Pädiatrische Pneumologie und Allergologie, Universitätsklinikum Gießen-Marburg GmbH, Gießen, Deutschland.
Britta SiegmundMedizinische Klinik für Gastroenterologie, Infektiologie, Rheumatologie (einschl. Ernährungsmedizin), Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Deutschland.
Georg ErtlDeutsches Zentrum für Herzinsuffizienz, Universitätsklinikum Würzburg, Würzburg, Deutschland.
Deutsche Gesellschaft für Innere Medizin (DGIM)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rare diseases, defined in the European Union as conditions affecting fewer than five per 10,000 inhabitants, often manifest themselves in childhood, but are playing an increasingly important role in internal medicine due to the significantly improved long-term prognosis and a number of diseases that primarily occur in adulthood. Although noteworthy structures already exist nationally and internationally (networks, registers, databases, self-help groups), awareness of these diseases in daily routine and knowledge of the partly divergent care structures must be improved. There are no specific treatments for many of these diseases, but drugs are increasingly being developed-particularly in oncology-that are subject to special orphan drug status.

Indexed as

Internal MedicineRare DiseasesAdultChildEuropean UnionHumansOrphan Drug ProductionDrugs, orphanRare diseases/diagnosisRare diseases/health care structuresReference networksTransition to adult care

Identifiers

PMID40272470
PMCPMC12053190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.