Evidence map›Paper›PMID 40272466›Full record

ArticleNeuroradiology2025

Assessing anemia in stroke patients through virtual non-contrast imaging with photon-counting detector CT: validation on supra-aortic vessel CT-Angiography.

Guilherme A Quint, Josua A Decker, Abraham Cortes, Ansgar Berlis, Christoph J Maurer

Abstract readValidation Study
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Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Guilherme A QuintDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Stenglinstraße 2, 86156, Augsburg, Germany.
Josua A DeckerDepartment of Diagnostic and Interventional Radiology, University Hospital Augsburg, Stenglinstraße 2, 86156, Augsburg, Germany.
Abraham CortesDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Stenglinstraße 2, 86156, Augsburg, Germany.
Ansgar BerlisDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Stenglinstraße 2, 86156, Augsburg, Germany.
Christoph J MaurerDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Augsburg, Stenglinstraße 2, 86156, Augsburg, Germany. Christoph.Maurer@uk-augsburg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAnemia is a common comorbidity in stroke patients, traditionally detected via blood tests. This study evaluates the feasibility of using virtual non-contrast (VNC) imaging from photon counting detector-CT (PCD-CT) angiography to detect anemia and identifies the optimal anatomical site for assessment. MATERIALS AND

methodsIn this retrospective study of 80 patients undergoing PCD-CT angiography of supra-aortic vessels, VNC series were analyzed at various anatomical sites, including the jugular veins, aorta, and cerebral sinuses. Correlations between serum hemoglobin (Hb) levels and VNC Hounsfield Unit (HU) values were assessed using Pearson's coefficients. Linear regression and ROC analysis evaluated diagnostic performance.ResultsThe jugular veins showed the strongest correlation between VNC HU values and Hb levels (R

conclusionsVNC imaging in CT angiography is a feasible method for detecting anemia, with the jugular veins providing the most reliable site for assessment. VNC imaging could be a valuable alternative when blood tests are delayed or unavailable.

Indexed as

AnemiaCerebral AngiographyComputed Tomography AngiographyStrokeAgedAged, 80 and overFeasibility StudiesFemaleHumansJugular VeinsMaleMiddle AgedRetrospective StudiesAnemia detectionPhoton-counting detector CTStrokeSupra-aortic vesselsVirtual-non-contrast-imaging

Identifiers

PMID40272466
PMCPMC12494657

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.