ArticleNeuroradiology2025
Thrombus perviousness in acute ischemic stroke: a scoping review of methodology, predictive value, and future perspectives.
Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Thrombus Perviousness Is Associated With Differential Treatment Outcomes Following IVT and EVT in MeVO Stroke.Stroke · 2026Article
- Prediction of functional outcome after mechanical thrombectomy using radiomics and deep learning features derived from intra-thrombus and peri-thrombus regions.Frontiers in neurology · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThrombus perviousness, depicting the interaction of occlusive clot with contrast media as measured with computed tomography (CT) is a relatively new imaging biomarker in acute ischemic stroke (AIS). This approach holds the potential to tailor revascularization strategies and post-interventional treatments, thereby enhancing functional outcomes. However, its predictive value is not yet conclusive despite its association with several clinical parameters.
methodsThis scoping review provides a comprehensive overview of 51 articles that explore this issue. It focuses on the analysis of applied methodology in measuring perviousness, the predictive value of perviousness based on available data, and the future perspectives and potentials this biomarker may have in AIS imaging.
resultsAlthough some data are contradictory, in the vast majority of published studies, pervious thrombi were easier to remove with mechanical thrombectomy, responded better to thrombolytic treatment and showed better functional outcome than impervious thrombi. The methodology of measuring perviousness is not yet standardized, which may lead to inconsistency in the findings. New data on time-resolved (dynamic) perviousness show more promising results and refined characterization of occlusive thrombi in AIS.
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