Evidence map›Paper›PMID 40271548›Full record

ReviewMolecular ecology2025

Mixed Outcomes in Recombination Rates After Domestication: Revisiting Theory and Data.

Madeline Bursell, Manav Rohilla, Lucia Ramirez, Yuhuan Cheng, Enrique J Schwarzkopf, Rafael F Guerrero, Caiti Smukowski Heil

Abstract readReview
In one paragraph

Review in Molecular ecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Madeline BursellDepartment of Plant Pathology and Entomology, North Carolina State University, Raleigh, North Carolina, USA.
Manav RohillaBioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA.
Lucia RamirezDepartment of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Yuhuan ChengBioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA.
Enrique J SchwarzkopfDepartment of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA.
Rafael F GuerreroBioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-8451-3609
Caiti Smukowski HeilDepartment of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA.

Funding

Recombination rate variation and evolutionR35GM142849 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SMUKOWSKI HEIL, CAITLIN SUZANNE · 2021 to 2025
$1.9M
Computational tools and quantitative analyses of genome structure evolutionR35GM147107 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Rafael F Guerrero · 2022 to 2026
$1.8M
NIGMS NIH HHS R35 GM142849NIGMS NIH HHS R35 GM147107
6 · The paper itself

Abstract

The process of domestication has altered many phenotypes. Selection on these phenotypes has long been hypothesised to indirectly select for increases in the genome-wide recombination rate. This hypothesis is potentially consistent with theory on the evolution of the recombination rate, but empirical support has been unclear. We review relevant theory, lab-based experiments, and data comparing recombination rates in wild progenitors and their domesticated counterparts. We utilise population sequencing data and a deep learning method to infer genome-wide recombination rates for new comparisons of chicken/red junglefowl, sheep/mouflon, and goat/bezoar. We find evidence of increased recombination in domesticated goats compared to bezoars but more mixed results in chicken and generally decreased recombination in domesticated sheep compared to mouflon. Our results add to a growing body of literature in plants and animals that finds no consistent evidence of an increase in genome-wide recombination with domestication.

Indexed as

Animals, DomesticDomesticationRecombination, GeneticAnimalsChickensGenetics, PopulationGoatsModels, GeneticPhenotypeSelection, GeneticSheepchickendomesticationgoatrecombinationsheep

Identifiers

PMID40271548
PMCPMC12353367

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.