Evidence map›Paper›PMID 40271538›Full record

ArticleTobacco regulatory science2019

Estimating Uptake for Reduced-nicotine Cigarettes Using Behavioral Economics.

Brent A Kaplan, Derek A Pope, William B DeHart, Jeffrey S Stein, Warren K Bickel, Mikhail N Koffarnus

Abstract read
In one paragraph

Article in Tobacco regulatory science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Effects of Reduced-Nicotine Cigarettes Across Regulatory Environments in the Experimental Tobacco Marketplace: A Randomized Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Trial
  2. Article
  3. Article
  4. Electronic Nicotine Delivery Devices Function as a Complement for Cigarillos in Sexual and Gender Minority Young Adult Women.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  5. E-cigarette Price Impacts legal and Black-Market Cigarette Purchasing Under a Hypothetical Reduced-Nicotine Cigarette Standard.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  6. Article
  7. Article
  8. Blood Nicotine Predicts the Behavioral Economic Abuse Liability of Reduced-Nicotine Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brent A KaplanFralin Biomedical Research Institute at VTC, Roanoke, VA.
Derek A PopeFralin Biomedical Research Institute at VTC, Roanoke, VA.
William B DeHartFralin Biomedical Research Institute at VTC, Roanoke, VA.
Jeffrey S SteinFralin Biomedical Research Institute at VTC.
Warren K BickelFralin Biomedical Research Institute at VTC, Roanoke, VA.
Mikhail N KoffarnusFralin Biomedical Research Institute at VTC, Roanoke, VA.

Funding

Abuse liability of reduced nicotine content cigarettes within a complex tobacco marketplaceR01DA042535 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BICKEL, WARREN K, KOFFARNUS, MIKHAIL NIKOLAAS · 2016 to 2018
$1.5M
NIDA NIH HHS R01 DA042535
6 · The paper itself

Abstract

Objectives: Lowering the nicotine content in combustible cigarettes may be a viable strategy for reducing dependence and toxin exposure. Understanding how marketing and education may affect initial uptake is an important avenue of inquiry prior to any policy change. There has yet to be an investigation of how framing reductions in nicotine may affect intentions to purchase and consume these cigarettes using the behavioral economic framework. Methods: Participants from Amazon Mechanical Turk completed several tasks, including the Cigarette Purchase Task and Experimental Tobacco Marketplace, under conditions in which a new, reduced-nicotine cigarette alternative is the only cigarette available. Results: Cigarette purchasing was largely unaffected by stated nicotine concentration, but lower concentrations suggested the potential of small estimated compensatory purchasing. Exposure to a narrative detailing how others have perceived the negative subjective effects of lower nicotine cigarettes (eg, less satisfaction) significantly reduced the perceived value of cigarettes. Conclusions: These results suggest information about nicotine content alone is unlikely to reduce initial uptake without accompanying narratives about the effects of this reduced-nicotine content.

Indexed as

behavioral economicscigarette purchase taskcigarettesdemandexperimental tobacco marketplacehumansnicotine reduction

Identifiers

PMID40271538
PMCPMC12017782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.