SynthesisFrontiers in bioengineering and biotechnology2025
Effect of collagen crosslinkers on sodium hypochlorite treated dentin bond strength: a systematic review and meta-analysis.
Synthesis in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Effect of resin infiltration and Er: YAG laser on the shear bond strength between glass ceramics and white spot lesions: an in vitro study.Clinical oral investigations · 2026Article
- Effects of phytic and tannic acids on dentin bonding, nanoleakage, and micropermeability under wet and dry bonding techniques.Odontology · 2026Article
- Effects and Properties of Deproteinizing Methods in Dentin: A Comprehensive Narrative Review.Journal of functional biomaterials · 2026Review
- Influence of Different Cavity Disinfection Protocols on Adhesion at the Resin Composite-Dentin Interface.Polymers · 2026Article
- Shear bond strength analysis of self-etch and total-etch adhesive systems on antioxidant-treated dentin in post-endodontic restoration.Frontiers in dental medicine · 2026Article
- Article
- Preendodontic Dentin Hybridization - Effect on Coronal Dentin Microhardness and Resin-Dentin Bond Strength: AnContemporary clinical dentistryArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The bond strength (BS) between composite resin and dentin is a crucial factor determining the long-term success of restorations. Sodium hypochlorite (NaOCl), a frequently used root canal irrigating agent, has been demonstrated to notably influence the properties of dentin, thereby affecting the BS. Moreover, the application of collagen crosslinkers has become a potential approach to improve the stability of the resin-dentin bond. Nevertheless, the effect of collagen crosslinkers on the bond strength (BS) between sodium hypochlorite (NaOCl) treated dentin and composite resin remains a topic of contention, and there is a lack of in-depth understanding in the existing literature. The purpose of this systematic review and meta-analysis was to analyze the current literature on the effect of collagen crosslinkers on the BS between sodium hypochlorite treated dentin and composite resin. Methods: Databases including PubMed, EMBASE, Cochrane library, Scopus, Web of Science and SinoMed were searched. Results: For dentin exposed less than 1 min or NaOCl at lower concentration, significant positive effect cannot be observed when using collagen crosslinkers. For dentin exposed more than 1 min in NaOCl at concentrations greater than 2.5%, EDTA, PA and SA were observed to significantly improve the BS. RA is proved effective in improving the BS of dentin exposed to high concentrations NaOCl within a shorter duration. Current evidence is insufficient to conclude that IP6 has a positive effect in NaOCl-treated dentin bonding performance. Conclusion: The effect of collagen crosslinkers on the BS of NaOCl treated dentin was influenced by the concentration of NaOCl and the duration of exposure.
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