ArticleCureus2025
Whipple Procedure vs. Distal Pancreatectomy: A Study on the Efficacy, Survival Rates, and Complication Rates in Patients With Pancreatic Cancer.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPancreatic cancer remains one of the most aggressive and challenging malignancies to treat, with limited options for curative interventions.
objectiveThe basic aim of the study is to find and compare the efficacy, survival rates, and complication rates of the Whipple procedure versus distal pancreatectomy in patients with pancreatic cancer. METHODOLOGY: This retrospective observational study was conducted at Pakistan Kidney and Liver Institute, Lahore. Patients were enrolled from November 2018 to November 2019. Data were collected from 30 patients. Data were collected from the patient's medical records to evaluate and compare the outcomes of the two surgical approaches. The 30 patients were categorized into two equal groups based on the surgical intervention they received.
resultsThe mean age was comparable between groups, with an overall mean of 59.5 years. Tumors in Group A (Whipple procedure) were larger on average (3.8 ± 1.2 cm) compared to Group B (distal pancreatectomy; 3.2 ± 1.1 cm). Lymph node involvement was observed in 16 (53.3%) patients overall, with Group A showing a slightly higher rate (nine, 60%) compared to Group B (seven, 46.7%). Additionally, Group A had a higher mean number of lymph nodes removed (18) than Group B (15), while comorbidities were reported in 11 (36.7%) patients overall. The study found that the readmission rate was higher in Group A at three (20%), compared to two (13.3%) in Group B, reflecting the more complex and challenging postoperative course associated with the Whipple procedure.
conclusionThe Whipple procedure, performed for pancreatic head tumors, offers better long-term survival but carries a higher risk of complications, including delayed gastric emptying and pancreatic fistulas. In contrast, distal pancreatectomy, used for tumors in the body or tail, is associated with lower surgical complexity and fewer complications but may have less favorable survival outcomes due to the later-stage presentation of these tumors. Additionally, the frequent need for splenectomy in distal pancreatectomy increases the risk of postoperative infections.
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